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Scorpion serotherapy during pregnancy protects rat offspring from harmful effects of venom. | LitMetric

Scorpion serotherapy during pregnancy protects rat offspring from harmful effects of venom.

Toxicon

Laboratory of Pharmacology, Butantan Institute, Av. Dr. Vital Brazil 1500, São Paulo, 05503-900, Brazil. Electronic address:

Published: December 2024

Despite the numerous incidents of scorpion envenoming worldwide, little is known about the effects of maternal venom exposure and serotherapy on fetal development. The impact of antivenom on pregnant rats envenomed by Tityus serrulatus venom was examined. The venom caused alterations in the development of the offspring, yet the antivenom protected against these adverse effects and does not cause harm in itself, indicating the potential benefits of serotherapy.

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Source
http://dx.doi.org/10.1016/j.toxicon.2024.108188DOI Listing

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