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Mimicking Nature: Effect of Architectural Design Inspired by Cancellous Bone on the Biological Response of hMSC Cultured on Titanium Scaffolds Fabricated by Laser Beam Powder Bed Fusion.
J Biomed Mater Res A
January 2025
Faculty of Materials Science and Engineering, Warsaw University of Technology, Warsaw, Poland.
Bone tissue regeneration can be affected by various architectonical features of 3D porous scaffold, for example, pore size and shape, strut size, curvature, or porosity. However, the design of additively manufactured structures studied so far was based on uniform geometrical figures and unit cell structures, which often do not resemble the natural architecture of cancellous bone. Therefore, the aim of this study was to investigate the effect of architectonical features of additively manufactured (aka 3D printed) titanium scaffolds designed based on microtomographic scans of fragments of human femurs of individuals of different ages on in vitro response of human bone-derived mesenchymal stem cells (hMSC).
View Article and Find Full Text PDFFirst Experience With a Novel Self-Expandable Valve for Mitral Annular Calcification Guided by Three-Dimensional Printing.
Catheter Cardiovasc Interv
January 2025
Department of Cardiovascular Surgery, Xijing Hospital, Air Force Medical University, Xi'an, Shaanxi, China.
Transcatheter mitral valve replacement (TMVR) may emerge as a surgical alternative for high-risk patients with severe mitral annular calcification (MAC), yet several questions remain to be addressed. We present the case of a 67-year-old high-risk female patient with severe MAC (MAC score = 8) and mitral stenosis (effective orifice area = 121.3 mm).
View Article and Find Full Text PDFEffect of post-processing on the surface, optical, mechanical, and dimensional properties of 3D-printed orthodontic clear retainers.
Clin Oral Investig
January 2025
School of Materials Science and Innovation, Faculty of Science, Mahidol University, Phuttamonthon 4 Road, Salaya, Phuttamonthon District, Nakhon Pathom, 73170, Thailand.
Objectives: To address the high surface roughness and poor optical properties of three-dimensional (3D) printed orthodontic clear retainers, an alternative post-processing protocol was investigated with the goal of achieving improved surface, optical, and mechanical properties while preserving dimensional accuracy.
Materials And Methods: Samples were prepared from two biocompatible methacrylate-based 3D-printing resins (Formlabs Dental LT Clear V2, NextDent OrthoFlex) and one thermoplastic material (Duran). For the 3D-printed resins, one group was post-processed by rinsing in isopropyl alcohol, while another group was centrifuged before post-curing in glycerine.
3D printed cacao-based formulations as nutrient carriers for immune system enhancement.
Curr Res Food Sci
December 2024
School of Pharmacy, Queen's University Belfast, 97 Lisburn Road, Belfast, BT9 7BL, UK.
Article Synopsis
- This study investigates using raw Greek honey in cacao-based materials for 3D printing, focusing on their physical properties and thermal stability.
- It finds that incorporating honey not only improves the nutritional value and taste but also enhances the delivery of Vitamin D3, which is known to support the immune system but is difficult to absorb.
- The research suggests that a 10% concentration of Lavender Honey is optimal for creating a stable and effective 3D-printed product, indicating the potential for these formulations in personalized health supplements and medicine.
Multi-center evaluation of the first, low-cost, open source and totally 3D-printed pediatric laparoscopic trainer.
Heliyon
December 2024
Department of Pediatric and Adolescent surgery, University Hospital of Rouen, 76000, Rouen, France.
Article Synopsis
- A study was conducted to develop and evaluate the Space Child Laparoscopic Trainer (SCLT), a low-cost, 3D-printed tool designed for pediatric laparoscopic training, to assess its effectiveness compared to a standard laparoscopic trainer (LT).
- The SCLT was created using a 3D printer, cost five euros, and took about 10 minutes to assemble, with various aspects of performance measured through tasks completed by surgical residents and experienced surgeons.
- Results showed that the learning speed for surgical tasks was slightly higher with the SCLT compared to the LT, indicating it may be an effective alternative for training, although further assessment on its non-inferiority suggested more research is needed.
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