Objective: To describe complications and outcomes in cats undergoing epicardial pacemaker (EP) implantation for artificial cardiac pacing and to investigate improvement in clinical signs and health-related quality of life (HRQoL) following surgery.
Methods: 39 client-owned cats that underwent EP placement. Medical records of 4 UK-based referral hospitals were searched and data reviewed retrospectively between July 2010 and December 2022. An HRQoL questionnaire was used to assess outcomes and HRQoL.
Results: The primary reasons for referral included collapsing episodes (n = 27) and bradycardia (31). Third-degree atrioventricular block (29 of 39) was the predominant indication for pacemaker placement. Intra- and postoperative complications were documented in 3 of 39 and 14 of 39 cats, respectively. All cats survived to discharge, and median follow-up time was 719 days (range, 9 to 2,285 days). Owners reported improvement in clinical signs, high level of satisfaction, and improved HRQoL.
Conclusions: Epicardial pacemaker placement effectively resolves clinical signs of bradyarrhythmias in cats, leading to significant improvements in HRQoL. Postoperative complications are common but do not impact the overall outcome. Cats undergoing EP placement have an excellent HRQoL with an improvement in clinical signs and a high level of owner satisfaction.
Clinical Relevance: Epicardial pacemaker placement is the current method of choice for cats showing clinical signs and requiring artificial cardiac pacing. Despite the occurrence of postoperative complications, these did not adversely impact overall outcomes, with high owner satisfaction reported.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.2460/javma.24.09.0586 | DOI Listing |
JAMA
January 2025
Department of Internal Medicine, Michigan Medicine, Ann Arbor.
JAMA Dermatol
January 2025
Department of Dermatology, University of Pennsylvania, Philadelphia.
Importance: Cutaneous chronic graft-vs-host disease (GVHD) is independently associated with morbidity and mortality after allogeneic hematopoietic cell transplant. However, the health-related quality-of-life (HRQOL) domains that are most important to patients are poorly understood.
Objective: To perform a concept elicitation study to define HRQOL in cutaneous chronic GVHD from the patient perspective and to compare experiences of patients with epidermal vs sclerotic disease.
JAMA Netw Open
January 2025
Division of Cancer Genetics and Prevention, Dana-Farber Cancer Institute, Boston, Massachusetts.
Importance: CHEK2 pathogenic and likely pathogenic variants (PVs) are common, and low-risk (LR) variants, p.I157T, p.S428F, and p.
View Article and Find Full Text PDFJAMA Netw Open
January 2025
Medical Oncology, The Ottawa Hospital Cancer Centre, University of Ottawa Faculty of Medicine, Ottawa, Ontario, Canada.
Importance: Evolving breast cancer treatments have led to improved outcomes but carry a substantial financial burden. The association of treatment costs with the cost-effectiveness of screening mammography is unknown.
Objective: To determine the cost-effectiveness of population-based breast cancer screening in the context of current treatment standards.
JAMA Netw Open
January 2025
Center for OCD and Related Disorders, Massachusetts General Hospital, Boston.
Importance: Obsessive-compulsive and related disorders (OCRDs) encompass various neuropsychiatric conditions that cause significant distress and impair daily functioning. Although standard treatments are often effective, approximately 60% of patients may not respond adequately, underscoring the need for novel therapeutic approaches.
Objective: To evaluate improvement in OCRD symptoms associated with glutamatergic medications as monotherapy or as augmentation to selective serotonin reuptake inhibitors, with a focus on double-blind, placebo-controlled randomized clinical trials (RCTs).
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!