AI Article Synopsis
- - The study analyzed the presence of polyphenols in carob pods from Southern Italy using a reliable LC-HRMS method, revealing high levels of Apigenin and Myricetin.
- - Significant variations in polyphenol content, especially in hesperidin and myricetin, were found between different sampling areas, indicating that geochemical and climatic factors influence these variations.
- - This research is the first to document the phenolic content of carob pods in this region after harvest and highlights their potential health benefits in preventing oxidative stress-related diseases.
Article Abstract
The presence of polyphenols was examined in carob pods () from Southern Italy 90 days after harvest by the validation of a reliable LC-HRMS method. A greater abundance of Apigenin (51490.22 ± 34399.16 μg/Kg) and Myricetin (24897.92 ± 108332.05 μg/Kg) compared to previous research works conducted in Mediterranean countries. Significant differences in the polyphenol content between sampling areas ( < 0.05) were observed, particularly differences in hesperidin and myricetin. These differences confirmed the role of geochemical and climatic conditions in the variation of polyphenol content. This study is a first regarding the phenolic content of carob pods from Southern Italy, confirming the presence of these substances even long after harvest and that carob pods are valuable sources of phenolic substances that may be useful in the prevention of diseases related to oxidative stress.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1080/14786419.2024.2429527 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Therapeutic Efficacy of the Inositol D-Pinitol as a Multi-Faceted Disease Modifier in the 5×FAD Humanized Mouse Model of Alzheimer's Amyloidosis.
Nutrients
December 2024
Grupo de Neuropsicofarmacología, Instituto de Investigación Biomédica de Málaga y Plataforma en Nanomedicina-IBIMA Plataforma BIONAND, Unidades Clínicas de Neurología y Salud Mental, 29010 Málaga, Spain.
Background/objectives: Alzheimer's disease (AD), a leading cause of dementia, lacks effective long-term treatments. Current therapies offer temporary relief or fail to halt its progression and are often inaccessible due to cost. AD involves multiple pathological processes, including amyloid beta (Aβ) deposition, insulin resistance, tau protein hyperphosphorylation, and systemic inflammation accelerated by gut microbiota dysbiosis originating from a leaky gut.
View Article and Find Full Text PDFCarob (Ceratonia siliqua) leaves: A comprehensive analysis of bioactive profile and health-promoting potential of an untapped resource.
Food Chem
December 2024
Department of Pharmacy, University of Salerno, 84084 Fisciano, Salerno, Italy; National Biodiversity Future Center (NBFC), 90133 Palermo, PA, Italy.
Article Synopsis
- Carob (Ceratonia siliqua) leaves were studied for their chemical makeup and health benefits, focusing on making carob farming more sustainable.
- Key components identified in the leaves include various types of galloylated glucoses and flavonol-glycosides, with high levels of bioactive compounds linked to antioxidant properties.
- The leaves showed strong inhibitory effects on enzymes related to diabetes and neurodegenerative diseases, suggesting they may help manage blood sugar levels with minimal side effects.
Detection of polyphenols in carob pods () from Southern Italy by a LC-HRMS method.
Nat Prod Res
November 2024
Dipartimento di scienze biomediche e biotecnologiche, Università degli studi di Catania, Catania, Italy.
Article Synopsis
- - The study analyzed the presence of polyphenols in carob pods from Southern Italy using a reliable LC-HRMS method, revealing high levels of Apigenin and Myricetin.
- - Significant variations in polyphenol content, especially in hesperidin and myricetin, were found between different sampling areas, indicating that geochemical and climatic factors influence these variations.
- - This research is the first to document the phenolic content of carob pods in this region after harvest and highlights their potential health benefits in preventing oxidative stress-related diseases.
Production of biosurfactant by using agro-food wastes and its application in petroleum sludge oil recovery.
J Environ Health Sci Eng
December 2024
Laboratory of Petroleum Biotechnology and Environment, Central Directorate Research and Development, Sonatrach, Boumerdes, Algeria.
The objective of this study is to utilize cost-effective renewable substrates derived from agro-food wastes for the production of biosurfactant by , which was isolated from petroleum sludge. Various agro-food waste materials, namely potato peelings (PP), rice cooking water (RW), biscuit by products (BB), carob pods (CP), and eggshells, were evaluated as nutrient sources for bacterial growth compared to a synthetic medium (SM). The results indicate that the medium comprising carob pods, potato peels supplemented with eggshells promoted the growth of the bacteria and the production of Biosurfactants at a rate of 150 mg/l and 140 mg/l respectively.
View Article and Find Full Text PDFCo-administration of Ceratonia siliqua extract nanoparticles promotes the oral bioavailability and neurotherapeutic efficacy of donepezil in a dementia model.
J Pharm Pharmacol
July 2024
Therapeutic Chemistry Department, Pharmaceutical Industries and Drug Research Institute, National Research Centre, Dokki 12622, Cairo, Egypt.
Background: This study aimed to assess the herb-drug interactions between crude/silver nanoparticle (SNP)-loaded carob extract (Car, NCar, respectively) and donepezil-HCl (DPZ) and their impact on neurotherapeutic outcomes in a dementia model.
Methods: Carob pods were subjected to ethanol extraction, and their phytoconstituents were chromatographically analysed. SNP-loaded extract was synthesized and characterized, and dementia-like symptoms were induced in Wistar rats by repeated dosing with 175 mg/kg AlCl3 for 60 days, after which the animals were treated with Car, NCar, DPZ, and combinations of Car/NCar-DPZ for 30 days.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!