AI Article Synopsis

  • The study aimed to compare the effects of argon-beam-coagulation (ABC) suture-free technique versus conventional suture technique on renal function after laparoscopic partial nephrectomy.
  • A total of 32 patients were involved, with the primary measure being the change in split renal function after 12 months, alongside various secondary outcomes including operative times and blood loss.
  • Results showed that the suture-free technique had significantly shorter operative and warm ischemia times, and resulted in less decrease in split renal function and estimated glomerular filtration rate (eGFR) compared to the conventional method.

Article Abstract

Objective: To determine whether argon-beam-coagulation (ABC) suture-free technique results in more favorable renal function than conventional suture technique after laparoscopic partial nephrectomy.

Methods: This study was a single-center, open-label randomized controlled study. A total of 32 patients with T1a renal tumor and R.E.N.A.L score ≤7 were recruited. The primary endpoint of the study was the absolute variation of the ipsilateral split renal function (SRF) at 12 months. The following secondary endpoints were addressed: the 1, 3, 6, and 12-months variation of eGFR; the 1, 3, 6-months variation of SRF; perioperative outcomes (including operative time, warm ischemia time, time to hemostasis, blood loss).

Results: The suture-free group had a significantly shorter operative time (90.4 ± 22.0 minutes vs. 117.8 ± 23.5 minutes, p = 0.003) and warm ischemia time (9.6 ± 4.7 minutes vs. 21.3 ± 8.3 minutes, p < 0.001) than the suture group. At the last follow-up, the change of ipsilateral SRF was 7.5 ± 5.1 ml/min for the suture-free group and 13.1 ± 6.7 ml/min for the suture group (p = 0.014). The change of eGFR demonstrated a similar trend (5.5 ± 4.4 ml/min vs. 12.6 ± 6.0 ml/min, p=0.001). Multivariate linear analysis confirmed that suture-free technique was associated with a less decrease of renal function.

Conclusions: Suture-free partial nephrectomy is a feasible technique for T1a renal masses and benefits long-term SRF and eGFR compared to conventional procedure.

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Source
http://dx.doi.org/10.1016/j.urolonc.2024.11.006DOI Listing

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