Thalamic dementia usually results from a bilateral paramedian thalamic infarction. We report a case with typical clinical and neuropsychological features of thalamic dementia, but with CT evidence of an unusual and asymmetrical location of ischemic lesions. Somatosensory evoked potential recordings were consistent with a left medial thalamic infarction, associated with a contralateral lesion, possibly at lemniscal level. This case suggests that thalamic dementia may develop following a unilateral paramedian thalamic infarction.
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Eur J Neurol
March 2025
Department of Neurology and Institute of Neurology, Institute of Neuroscience, and Fujian Key Laboratory of Molecular Neurology, The First Affiliated Hospital of Fujian Medical University, Fuzhou, China.
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March 2025
Memory and Aging Center, Department of Neurology, UCSF Weill Institute for Neurosciences, University of California, San Francisco, California, USA.
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March 2025
UK Dementia Research Institute - Care Research and Technology Centre, Imperial College London, London, United Kingdom; Department of Brain Sciences, Imperial College London, London, United Kingdom. Electronic address:
Brain atrophy is detected in early Parkinson's disease (PD) and accelerates over the first few years post-diagnosis. This was captured by multiple cross-sectional studies and a few longitudinal studies in early PD. Yet only a longitudinal study with a control group can capture accelerated atrophy in early PD and differentiate it from healthy ageing.
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Department of Electrical Engineering, Indian Institute of Technology Delhi, New Delhi, India.
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View Article and Find Full Text PDFNat Neurosci
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Momentum Laboratory of Neuroimmunology, HUN-REN Institute of Experimental Medicine, Budapest, Hungary.
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