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Ugeskr Laeger

Afdeling for Infektionssygdomme, Aarhus Universitetshospital.

Published: November 2024

AI Article Synopsis

  • A 37-year-old woman was hospitalized with fever and muscle pain after returning from Mauritius.
  • She developed severe respiratory and circulatory failure shortly after receiving intravenous ceftriaxone, with anaphylaxis and pulmonary embolism being ruled out.
  • Ultimately, she tested positive for leptospirosis, and her critical condition was attributed to a Jarisch-Herxheimer reaction.

Article Abstract

In this case report, a 37-year-old female was admitted to hospital with fever and muscle pain two days after returning from Mauritius. Approximately two hours after first administration of intravenous ceftriaxone she suddenly developed respiratory and circulatory failure. Anaphylaxis and pulmonary embolism were considered and excluded. Initially she was treated as having sepsis and required respiratory and vasopressor support. She ended up testing positive for leptospirosis and it was concluded that the respiratory and circulatory failure was a Jarisch-Herxheimer reaction.

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Source
http://dx.doi.org/10.61409/V06240398DOI Listing

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