Optical aberrations prevent telescopes from reaching their theoretical diffraction limit. Once estimated, these aberrations can be compensated for using deformable mirrors in a closed loop. Focal plane wavefront sensing enables the estimation of the aberrations on the complete optical path, directly from the images taken by the scientific sensor. However, current focal plane wavefront sensing methods rely on physical models whose inaccuracies may limit the overall performance of the correction. The aim of this study is to develop a data-driven method using model-free reinforcement learning to automatically perform the estimation and correction of the aberrations, using only phase diversity images acquired around the focal plane as inputs. We formulate the correction problem within the framework of reinforcement learning and train an agent on simulated data. We show that the method is able to reliably learn an efficient control strategy for various realistic conditions. Our method also demonstrates robustness to a wide range of noise levels.
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http://dx.doi.org/10.1364/OE.529415 | DOI Listing |
J Med Internet Res
January 2025
ETH Zurich, Zurich, Switzerland.
Background: The escalating global scarcity of skilled health care professionals is a critical concern, further exacerbated by rising stress levels and clinician burnout rates. Artificial intelligence (AI) has surfaced as a potential resource to alleviate these challenges. Nevertheless, it is not taken for granted that AI will inevitably augment human performance, as ill-designed systems may inadvertently impose new burdens on health care workers, and implementation may be challenging.
View Article and Find Full Text PDFPLoS One
January 2025
Faculty of Philosophy, Department of Psychology, University of Novi Sad, Novi Sad, Serbia.
Virtual reality (VR) provides a unique opportunity to simulate various environments, enabling the observation of human behavior in a manner that closely resembles real-world scenarios. This study aimed to explore the effects of anticipating reward or punishment, personality traits, and physiological arousal on risky decision-making within a VR context. A custom VR game was developed to simulate real-life experiences.
View Article and Find Full Text PDFSong acquisition behavior observed in the songbird system provides a notable example of learning through trial- and-error which parallels human speech acquisition. Studying songbird vocal learning can offer insights into mechanisms underlying human language. We present a computational model of song learning that integrates reinforcement learning (RL) and Hebbian learning and agrees with known songbird circuitry.
View Article and Find Full Text PDFCureus
December 2024
SimTiki Simulation Center, John A. Burns School of Medicine, University of Hawai'i at Mānoa, Honolulu, USA.
Introduction Debriefing in healthcare simulation is helpful in reinforcing learning objectives, closing performance gaps, and improving future practice and patient care. The Debriefing Assessment for Simulation in Healthcare (DASH) is a validated tool. However, localized rater training for the DASH has not been described.
View Article and Find Full Text PDFiScience
January 2025
Department of Bioscience and Bioinformatics, Kyushu Institute of Technology, 680-4 Kawazu, Iizuka, Fukuoka 820-8502, Japan.
Drugs that interact with multiple therapeutic targets are potential high-value products in polypharmacology-based drug discovery, but the rational design remains a formidable challenge. Here, we present artificial intelligence (AI)-based methods to design the chemical structures of compounds that interact with multiple therapeutic target proteins. The molecular structure generation is performed by a fragment-based approach using a genetic algorithm with chemical substructures and a deep learning approach using reinforcement learning with stochastic policy gradients in the framework of generative adversarial networks.
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