Background: There is lack of knowledge and awareness about HRT use in non-gynaecological cancer survivors. The decision to advocate or discourage HRT in such women depends on various factors, including cancer type, hormone sensitivity, and individual patient characteristics. The paucity of available good quality clinical evidence and epidemiological data leads to lack of consensus in such cases. This article aims to address this knowledge gap by conducting a comprehensive qualitative analysis of the existing literature pertaining to HRT use in non-gynaecological cancer survivors.
Materials And Methods: We conducted a literature review. A systematic review was not possible because of lack of good quality research. We excluded case reports.
Results: A total of 55 papers were identified and all of these have been referenced. We have presented the inconsistencies and uncertainties in the evidence available from the limited information available from cohort studies.
Conclusion: Prescription of HRT in cancer survivors of many hormone dependent non-gynaecological cancers needs careful consideration of histology of the cancer and consideration about liaison with the concerned oncology team.
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http://dx.doi.org/10.1177/20533691241304028 | DOI Listing |
Post Reprod Health
December 2024
Obstetrics and Gynaecology, Wrexham Maelor Hospital, Betsi Cadwaladr University Health Board, Wrexham, North Wales.
Background: There is lack of knowledge and awareness about HRT use in non-gynaecological cancer survivors. The decision to advocate or discourage HRT in such women depends on various factors, including cancer type, hormone sensitivity, and individual patient characteristics. The paucity of available good quality clinical evidence and epidemiological data leads to lack of consensus in such cases.
View Article and Find Full Text PDFEur J Contracept Reprod Health Care
April 2024
Department of Women's and Children's Health, Karolinska Institutet, Stockholm, Sweden.
Purpose: This review presents an update of the non-contraceptive health benefits of the combined oral contraceptive pill.
Methods: We conducted a literature search for (review) articles that discussed the health benefits of combined oral contraceptives (COCs), in the period from 1980 to 2023.
Results: We identified 21 subjective and/or objective health benefits of COCs related to (i) the reproductive tract, (ii) non-gynaecological benign disorders and (iii) malignancies.
BMJ Case Rep
September 2023
Department of Obstetrics and Gynecology, University of Nebraska Medical Center, Omaha, Nebraska, USA.
Many conditions that affect a woman's health can be evaluated through the pelvic examination. Early detection and treatment of a range of gynaecologic and non-gynaecological conditions, including unusual pelvic masses, may decrease a woman's morbidity and mortality. Here, we have a female patient in her early 20s who was found to have a mass on her first screening pelvic examination.
View Article and Find Full Text PDFBr J Surg
August 2023
Department of Psychiatry, Massachusetts General Hospital, Boston, Massachusetts, USA.
Front Oncol
August 2022
Department of Gynaecology and Obstetrics, University Medical Centre, Johannes Gutenberg University Mainz, Mainz, Germany.
Objective: Serous tubal intraepithelial carcinoma (STIC) is a precursor lesion of pelvic high-grade serous carcinoma (HGSC). Information on treatment and outcome of isolated STIC is rare. Therefore, we reviewed systematically the published literature to determine the incidence of subsequent HGSC in the high- and low-risk population and to summarize the current diagnostic and therapeutic options.
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