We report encapsulated papillary carcinoma and mucinous carcinoma in a case of local advanced bilateral breast cancer. The patient was 78-year-old woman who had bilateral breast tumor. The right palpable tumor was 6 cm in diameter and left tumor was 7 cm in a diameter. Ultrasonography revealed a low echoic mass in both side breast. A core needle biopsy was performed for the bilateral tumor. Pathological diagnoses were suspicious of papillary carcinoma(right side), mucinous carcinoma(left side). She underwent a bilateral total mastectomy and sentinel lymph node biopsy. The final permanent pathological diagnoses were encapsulated papillary carcinoma(right side)and mixed type mucinous carcinoma(left side). After operation, she was administrated an aromatase inhibitor. The patient has been well and remained disease-free during a follow-up period of 1 years. The surgical excision was useful for locally advanced breast cancer patients who were possible to perform operation.

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