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Utilization of kidneys from tuberculosis-infected donors in renal transplantation: A case report. | LitMetric

Utilization of kidneys from tuberculosis-infected donors in renal transplantation: A case report.

Transpl Immunol

Department of Organ Transplantation, Renmin Hospital of Wuhan University, 238 Jiefang Road, Wuhan 430060, China; Department of Urology, Renmin Hospital of Wuhan University, Wuhan 430060, Hubei, PR China. Electronic address:

Published: November 2024

AI Article Synopsis

Article Abstract

Tuberculosis (TB) infection in solid organ transplantation is a non-negligible problem in TB-endemic countries, and none of the existing guidelines recommend using organs from individuals with active TB infections. Here, we describe three cases of utilization of kidneys from TB-infected donors in renal transplantation at our center, two of whom had active TB. In these three cases, all recipients had good graft function and negative TST results during the 1-4 year follow-up period. This case report emphasizes the critical role of early diagnosis, prophylaxis and treatment of TB in renal transplantation, demonstrates the potential for utilizing kidneys from donors with active TB, and opens up a new possibilities for solid organ transplantation.

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Source
http://dx.doi.org/10.1016/j.trim.2024.102151DOI Listing

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