When drying hands with a high-speed air jet dryer, the jet impingement on hands can quickly atomize the remnant water on the hand skins into droplets and aerosols. Emission of droplets and liquid aerosols, their spatial transport and the possible inhaling exposure to the hand dryer user remain unclear. This investigation measured the jet flows from a downward air jet dryer, by the particle image velocimetry (PIV), the helium bubble trajectory analysis, and an ultrasonic anemometer. Emission of the droplets when turning over the hands, the droplet spatial motion, and their deposition on human body were photographed by a high speed camera. Concentrations of the liquid aerosols were monitored and the total emitted aerosol numbers and size spectrum were analyzed. The possible inhalation exposure to the emitted liquid aerosols was examined. It is found that number of droplets in size of 0.1 to 0.6 mm can deposit on the mouth and nose and the surrounding face. A typical hand drying process may emit approximately 10 liquid aerosols, of which 93 % are in the submicron size. A hand dryer user may inhale thousands of the emitted liquid aerosols if drying hands without wearing face mask.
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http://dx.doi.org/10.1016/j.jhazmat.2024.136508 | DOI Listing |
Acc Chem Res
January 2025
Chemical Sciences Division, Lawrence Berkeley National Laboratory, Berkeley, California 94720, United States.
ConspectusReactions of gas phase molecules with surfaces play key roles in atmospheric and environmental chemistry. Reactive uptake coefficients (γ), the fraction of gas-surface collisions that yield a reaction, are used to quantify the kinetics in these heterogeneous and multiphase systems. Unlike rate coefficients for homogeneous gas- or liquid-phase reactions, uptake coefficients are system- and observation-dependent quantities that depend upon a multitude of underlying elementary steps.
View Article and Find Full Text PDFJ Aerosol Med Pulm Drug Deliv
January 2025
Department of Mechanical Engineering, University of Alberta, Edmonton, Canada.
Dry powders offer the potential to increase stability and reduce cold-chain requirements associated with the distribution of vaccines and other thermally sensitive products. The Alberta Idealized Nasal Inlet (AINI) is a representative geometry for characterization of nasal products that may prove useful in examining intranasal delivery of powders. Spray-dried trehalose powders were loaded at 10, 20, and 40 mg doses into active single-dose devices.
View Article and Find Full Text PDFThis study describes a complex human in vitro model for evaluating anti-inflammatory drug response in the alveoli that may contribute to the reduction of animal testing in the pre-clinical stage of drug development. The model is based on the human alveolar epithelial cell line Arlo co-cultured with macrophages differentiated from the THP-1 cell line, creating a physiological biological microenvironment. To mimic the three-dimensional architecture and dynamic expansion and relaxation of the air-blood-barrier, they are grown on a stretchable microphysiological lung-on-chip.
View Article and Find Full Text PDFPharmaceutics
December 2024
Department of Pharmaceutical Sciences, College of Pharmacy, QU Health Sector, Qatar University, Doha 2713, Qatar.
Background/objectives: This study aimed to fabricate, optimize, and characterize nanostructured lipid carriers (NLCs) loaded with trans-resveratrol (TRES) as an anti-cancer drug for pulmonary drug delivery using medical nebulizers.
Methods: Novel TRES-NLC formulations (F1-F24) were prepared via hot, high-pressure homogenization. One solid lipid (Dynasan 116) was combined with four liquid lipids (Capryol 90, Lauroglycol 90, Miglyol 810, and Tributyrin) in three different ratios (10:90, 50:50, and 90:10 /), with a surfactant (Tween 80) in two different concentrations (0.
Microorganisms
December 2024
School of Life Sciences, University of Essex, Wivenhoe Park, Colchester, CO4 3SQ, UK.
Multiple human and plant pathogens are dispersed and transmitted as bioaerosols (e.g., , SARS-CoV-2, , , spp.
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