AI-driven segmentation of the pulp cavity system in mandibular molars on CBCT images using convolutional neural networks.

Clin Oral Investig

OMFS-IMPATH Research Group, Department of Imaging and Pathology, Faculty of Medicine, KU Leuven, Kapucijnenvoer 7, Leuven, 3000, Belgium.

Published: November 2024

AI Article Synopsis

  • A study developed and validated an AI tool for automatically segmenting the pulp cavity of mandibular molars from cone-beam CT images, dividing data into training, validation, and testing sets for evaluation.
  • The AI tool demonstrated high accuracy in segmentation, with Dice similarity coefficients of 88% for first molars and 90% for second molars, while also significantly reducing time needed for segmentation compared to manual methods.
  • This AI-driven method can enhance efficiency in endodontic procedures by providing quick, accurate 3D models, potentially improving patient outcomes and anticipating complications.

Article Abstract

Objective: To develop and validate an artificial intelligence (AI)-driven tool for automated segmentation of the pulp cavity system of mandibular molars on cone-beam computed tomography (CBCT) images.

Materials And Methods: After ethical approval, 66 CBCT scans were retrieved from a hospital database and divided into training (n = 26, 86 molars), validation (n = 7, 20 molars), and testing (n = 33, 60 molars) sets. After automated segmentation, an expert evaluated the quality of the AI-driven segmentations. The expert then refined any under- or over-segmentation to produce refined-AI (R-AI) segmentations. The AI and R-AI 3D models were compared to assess the accuracy. 30% of the testing sample was randomly selected to assess accuracy metrics and conduct time analysis.

Results: The AI-driven tool achieved high accuracy, with a Dice similarity coefficient (DSC) of 88% ± 7% for first molars and 90% ± 6% for second molars (p > .05). The 95% Hausdorff distance (HD) was lower for AI-driven segmentation (0.13 ± 0.07) compared to manual segmentation (0.21 ± 0.08) (p < .05). Regarding time efficiency, AI-driven (4.3 ± 2 s) and R-AI segmentation (139 ± 93 s) methods were the fastest, compared to manual segmentation (2349 ± 444 s) (p < .05).

Conclusion: The AI-driven segmentation proved to be accurate and time-efficient in segmenting the pulp cavity system in mandibular molars.

Clinical Relevance: Automated segmentation of the pulp cavity system may result in a fast and accurate 3D model, facilitating minimal-invasive endodontics and leading to higher efficiency of the endodontic workflow, enabling anticipation of complications.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11582138PMC
http://dx.doi.org/10.1007/s00784-024-06009-2DOI Listing

Publication Analysis

Top Keywords

ai-driven segmentation
8
segmentation pulp
8
pulp cavity
8
cavity system
8
system mandibular
8
mandibular molars
8
ai-driven tool
8
automated segmentation
8
assess accuracy
8
molars
7

Similar Publications

Microscopic imaging aids disease diagnosis by describing quantitative cell morphology and tissue size. However, the high spatial resolution of these images poses significant challenges for manual quantitative evaluation. This project proposes using computer-aided analysis methods to address these challenges, enabling rapid and precise clinical diagnosis, course analysis, and prognostic prediction.

View Article and Find Full Text PDF

Pancreatic ductal adenocarcinoma (PDAC) is the third leading cause of cancer-related deaths in the United States, largely due to its poor five-year survival rate and frequent late-stage diagnosis. A significant barrier to early detection even in high-risk cohorts is that the pancreas often appears morphologically normal during the pre-diagnostic phase. Yet, the disease can progress rapidly from subclinical stages to widespread metastasis, undermining the effectiveness of screening.

View Article and Find Full Text PDF

A prospectively deployed deep learning-enabled automated quality assurance tool for oncological palliative spine radiation therapy.

Lancet Digit Health

January 2025

Department of Radiation Oncology, Brigham and Women's Hospital, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA; Artificial Intelligence in Medicine (AIM) Program, Mass General Brigham, Harvard Medical School, Boston, MA, USA. Electronic address:

Background: Palliative spine radiation therapy is prone to treatment at the wrong anatomic level. We developed a fully automated deep learning-based spine-targeting quality assurance system (DL-SpiQA) for detecting treatment at the wrong anatomic level. DL-SpiQA was evaluated based on retrospective testing of spine radiation therapy treatments and prospective clinical deployment.

View Article and Find Full Text PDF

An integrated microflow cytometry platform with artificial intelligence capabilities for point-of-care cellular phenotype analysis.

Biosens Bioelectron

March 2025

Department of Biotechnology, National Formosa University, No. 64, Wunhua Rd, Huwei Township, Yunlin County, 63201, Taiwan. Electronic address:

The EZ DEVICE is an integrated fluorescence microflow cytometer designed for automated cell phenotyping and enumeration using artificial intelligence (AI). The platform consists of a laser diode, optical filter, objective lens, CMOS image sensor, and microfluidic chip, enabling automated sample pretreatment, labeling, and detection within a single compact unit. AI algorithms segment and identify objects in images captured by the CMOS sensor at 532 and 586 nm emission wavelengths.

View Article and Find Full Text PDF

Background: Fully automatic skull-stripping and tumor segmentation are crucial for monitoring pediatric brain tumors (PBT). Current methods, however, often lack generalizability, particularly for rare tumors in the sellar/suprasellar regions and when applied to real-world clinical data in limited data scenarios. To address these challenges, we propose AI-driven techniques for skull-stripping and tumor segmentation.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!