Selective C-H functionalization methods could provide a valuable tool for synthesizing different steroid derivatives, which is essential not only in contexts of developing novel synthetic methodology but also as a direct way for gathering the analogues needed for studying the structure-activity relationships and obtaining biologically active compounds. The review discusses recent examples of steroid C-H functionalization to various C-X derivatives (C-O, C-C, C-N, C-S, and C-halogen) using available methods emphasizing their scope and limitations.
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