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Epidemiology and pathogen characteristics of infections following solid organ transplantation. | LitMetric

AI Article Synopsis

  • Solid organ transplantation (SOT) recipients face increased infection risks due to ongoing use of immunosuppressive drugs, and these risks vary by organ type and other factors.
  • The most commonly transplanted organ is the kidney, followed by the liver, heart, and lung; each has different rates and types of post-transplant infections, including bacterial, fungal, and viral.
  • The review aims to analyze the epidemiology of infections across different SOTs and seeks to improve patient care by developing tailored prevention strategies to enhance the quality of life for transplant recipients.

Article Abstract

Solid organ transplantation (SOT) recipients have a heightened risk for infection due to prolonged immunosuppressive drug use following transplant procedures. The occurrence of post-transplant infections is influenced not only by the transplanted organ type but also by varied factors. The kidney is the most common organ in SOT, followed by the liver, heart, and lung. This review aims to provide a comprehensive overview of the current epidemiological characteristics of infections after kidney, liver, heart, and lung transplantation, focusing on bacterial, fungal, and viral infections. The incidence and infection types demonstrated significant variability across different SOTs. Furthermore, this review attempts to elucidate the clinical characteristics of infections across patients following different SOTs and contribute to the development of individualized prevention strategies according to infection incidence, ultimately enhancing the quality of life of transplant recipients.

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Source
http://dx.doi.org/10.1093/jambio/lxae292DOI Listing

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