AI Article Synopsis
- Cyclodextrins and their derivatives are widely used in pharmaceuticals, cosmetics, and food due to their unique properties.
- Monosubstituted cyclodextrin derivatives are easier to synthesize, while di-substituted derivatives face challenges like low yields and difficult purification.
- This study introduces a new method for synthesizing di-substituted cyclodextrin derivatives that achieves a 33% yield without requiring chromatography, simplifying the process for larger applications.
Article Abstract
Cyclodextrins and their derivatives have extensive applications across pharmaceuticals, cosmetics, and the food industry due to their unique hydrophobic cavities. While monosubstituted cyclodextrin derivatives have established synthesis protocols, di-substituted derivatives pose significant challenges, including low yields and complex purification processes. This study presents a novel methodology for synthesizing di-substituted cyclodextrin derivatives, achieving a 33 % yield without relying on chromatographic techniques. This new approach streamlines the synthesis and purification process, making it more practical for large-scale applications and enhancing the utility of cyclodextrin derivatives in various industries.
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| http://dx.doi.org/10.1016/j.carbpol.2024.122926 | DOI Listing |
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