AI Article Synopsis
- Bone mineral density significantly decreases after spinal cord injuries, starting soon after paralysis begins and accelerating rapidly.
- A variety of factors contribute to this bone loss, including mechanical, neurological, hormonal, blood vessel-related, and medication influences.
- Dual x-ray absorptiometry is a cost-effective method to measure bone density changes, and while treatments exist to help prevent or reverse bone loss, their effectiveness can vary.
Article Abstract
A marked decrease in bone mineral density is a well recognized, if not always fully addressed, spinal cord injury-related comorbidity. The bone loss starts shortly after paralysis onset, and the loss rate is steep. The diverse etiology includes mechanical, neurologic, endocrine, vascular, and pharmacologic factors. Dual x-ray absorptiometry is available and affordable to quantify the degree of bone loss and follow changes related to treatment. Fragility/low impact fractures occur frequently and can induce significant morbidity. Physical modalities and pharmacologic interventions can be employed to stave off and/or reverse bone loss with variable success rates.
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| http://dx.doi.org/10.1016/j.pmr.2024.07.007 | DOI Listing |
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