AI Article Synopsis
- * Controlling postprandial glucose levels through diet is vital for preventing and managing T2DM, highlighting the importance of understanding dietary impacts on blood sugar regulation.
- * Dietary polyphenols (DPs) found in fruits and vegetables may help lower high postprandial glucose, with mechanisms like enhancing glucose transporters and activating metabolic pathways discussed as potential therapeutic strategies.
Article Abstract
Poor dietary intake or unhealthy lifestyle contributes to various health disorders, including postprandial hyperglycemia, leading to type 2 diabetes mellitus (T2DM). Reduction of postprandial glucose concentrations through diet is a key strategy for preventing and managing T2DM. Thus, it is essential to understand how dietary components affect glycemic regulation. Dietary polyphenols (DPs), such as anthocyanins and other phenolics found in various fruits and vegetables, are often recommended for their potential health benefits, although their systemic effectiveness is subject to ongoing debate. Therefore, this review assesses the current and historical evidence of DPs bioactivities, which regulate crucial metabolic markers to lower postprandial hyperglycemia. Significant bioactivities such as modulation of glucose transporters, activation of AMP kinase, and regulation of incretins are discussed, along with prospects for diet-induced therapeutics to prevent the onset of T2DM.
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| http://dx.doi.org/10.1016/j.advnut.2024.100346 | DOI Listing |
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