Many estuaries, including Chesapeake Bay, have suffered from undesirable conditions of algae blooms, poor water clarity, and low dissolved oxygen (DO). To better understand the status and trends of DO criteria attainment deficit (AD), we conducted a comprehensive assessment using monitoring data in the period of 1985-2022 and focused on the comparison of trends among 13 tidal systems. Our results provide timely and updated information to help address a critical management question, i.e., where has the DO criteria attainment improved since 1985? The overall AD showed statistically significant improvements in both the long term (1985-2022) and the short term (2006-2022), which can be mainly attributed to open water and deep channel designated uses, respectively. Among the 13 tidal systems, ten showed improving trends in the long term, with Mainstem Bay, Pocomoke, Potomac, and Tangier having statistically significant improvements. Over the short term, nine systems showed improving trends, with Chester and Upper Mainstem Bay tributaries having statistically significant improvements. The only statistically significant degrading trend was observed in York. In addition, a report card summary was produced to provide a concise depiction of the trends for the 13 systems and illustrate how their trends are affected by the designated uses, which is the first of its kind in the context of DO criteria assessment. These spatially explicit results can help target locations for further assessment and restoration. Although many of the systems and their applicable designated uses have not improved over time, the detected significant improvements in some systems present new evidence on ecosystem recovery in the context of DO criteria attainment. Overall, this work highlights the combined value of collecting long-term water-quality monitoring data and developing scientific assessment approaches, which is fundamental to understanding the status and trends of complex ecosystems, including Chesapeake Bay and other estuaries.
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http://dx.doi.org/10.1016/j.scitotenv.2024.177617 | DOI Listing |
J Clin Neurosci
January 2025
Lausanne University Hospital (CHUV), Neurosurgery Service and Gamma Knife Center, Switzerland; University of Lausanne (UNIL), Faculty of Biology and Medicine (FBM), Switzerland; Ecole Polytechnique Fédérale de Lausanne (EPFL, LTS-5), Switzerland. Electronic address:
Introduction: Stereotactic radiosurgery (SRS) is one of the treatment options for the management of residual or recurrent secreting pituitary adenomas (PA). While the role of radiosurgery (RS) by Gamma Knife (GK) has been clearly established, Cyberknife (CK) RS has been evaluated in fewer series.
Material And Methods: To perform a systematic review of the literature and meta-analysis, with the aim of focusing on the effect of CK RS on secreting PA.
Background: Adherence to self-care behaviors can prevent or delay adverse outcomes associated with cardiovascular disease (CVD). Sex and socioculturally constructed gender might impact individuals' ability to adhere to healthy lifestyles.
Objective: The aim of this study was to systematically identify, evaluate, and synthesize the literature on the influence of sex and gender on adherence to self-care behaviors for CVD risk management in the global context.
Ther Drug Monit
January 2025
Department of Pediatrics, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.
Background: Therapeutic drug monitoring-informed teicoplanin dosage adjustments are recommended for safe and effective use. The authors' group previously reported that only half of children reached the recommended blood concentration range at the standard teicoplanin loading dose. It has been suggested that higher loading doses are necessary; however, the usefulness and safety of high-dose loading in pediatric patients in clinical practice are unknown.
View Article and Find Full Text PDFJ Alzheimers Dis
January 2025
Department of Neurology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong, P.R. China.
Background: Cognitive reserve (CR), typically measured through socio-behavioral proxies, can partially explain better cognitive performance despite underlying brain aging or neuropathology.
Objective: To examine the associations of CR with mild cognitive impairment (MCI) and cognitive function while considering Alzheimer's disease (AD)-related plasma biomarkers.
Methods: This population-based cross-sectional study included 4706 dementia-free individuals from MIND-China.
Clin Kidney J
January 2025
Pharmacoepidemiology Unit, Department of Clinical Pharmacology, Amiens-Picardie University Medical Center, Amiens, France.
Background: We sought to comprehensively describe drug-related components associated with acute kidney injury (AKI) in patients with chronic kidney disease (CKD), describing the incidence of drug-related AKI, the proportion of preventable AKI, identified the various drugs potentially associated with it, explored the risk factors, and assessed the 1-year incidences of the recurrence of drug-related AKI, kidney failure, and death.
Methods: CKD-REIN is a French national prospective cohort of 3033 nephrology outpatients with a confirmed diagnosis of CKD (eGFR <60 ml/min/1.73 m²).
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