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Multi-Targeting Phytochemicals for Alzheimer's Disease.
Phytother Res
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Department of Pharmaceutical Sciences, Hemwati Nandan Bahuguna Garhwal University (A Central University), Srinagar, Uttarakhand, India.
Alzheimer's disease (AD) is a type of neurodegenerative illness in which β-amyloid (Aβ) and tau protein accumulate in neurons in the form of tangles. The pathophysiological pathway of AD consists of Aβ-amyloid peptides, tau proteins, and oxidative stress in neurons and increased neuro-inflammatory response. Food and Drug Administration in the United States has authorized various drugs for the effective treatment of AD, which include galantamine, rivastigmine, donepezil, memantine, sodium oligomannate, lecanemab, and aducanumab.
View Article and Find Full Text PDFAnalysis of Method Performance for Quantitative Assessment of Listeria monocytogenes in Queso Fresco Cheese.
J Food Prot
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QuoData GmbH, Dresden, Germany.
A Proficiency Test (PT) was conducted for Food Emergency Response Network (FERN) laboratories for quantitative assessment of Listeria monocytogenes (L. monocytogenes) in queso fresco cheese. The Moffett Proficiency Test Laboratory: MPTL (organizer) prepared test samples for each participating laboratory with 10 CFU/g of L.
View Article and Find Full Text PDFApproach to the Patient with Achondroplasia - New Considerations for Diagnosis, Management and Treatment.
J Clin Endocrinol Metab
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Division of Orthogenetics, Department of Pediatrics, Nemours Children's Hospital, Delaware, 1600 Rockland Road, Wilmington, DE, 19803, USA.
Achondroplasia is the most common disproportionate short-stature skeletal dysplasia. Features associated with achondroplasia are rhizomelia, macrocephaly, midface hypoplasia, and typical cognition. Potential medical complications include foramen magnum stenosis, hydrocephalus, middle ear dysfunction, obstructive and central sleep apnea, spinal stenosis and genu varum.
View Article and Find Full Text PDFPopulation exposure-response analysis of the effect of ritlecitinib on eyebrow assessment and eyelash assessment in patients with alopecia areata.
CPT Pharmacometrics Syst Pharmacol
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Pfizer Inc., Paris, France.
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View Article and Find Full Text PDFBreathing Transition and Effective Iodine Adsorption in a Temperature-Responsive Zn-Based Flexible Metal-Organic Framework.
Langmuir
January 2025
Department of Applied Chemistry, Aligarh Muslim University, Aligarh, 202002, India.
A porous and flexible Zn-MOF was synthesized under solvothermal conditions by using the ligand 2,5-furandicarboxylic acid (2,5-FDA). This flexible Zn-MOF demonstrates a temperature-triggered breathing effect. At low temperature (100 K), we obtained the high-symmetry MOF denoted as with a unit cell volume of 1958 Å, characterized by triangular narrow pore (np) channels.
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