AI Article Synopsis
- This study focused on identifying factors linked to status epilepticus (SE) in children after their first convulsive seizure, as SE can be a life-threatening condition.
- Out of 300 patients analyzed, a significant percentage experienced generalized seizures, with a notable occurrence of SE in almost a third of cases and various neurological abnormalities detected through EEG and MRI.
- Key risk factors for SE recurrence included being under 1 year old, having neuromotor delays, and abnormalities in EEG and MRI, while simple febrile seizures appeared to reduce the risk.
Article Abstract
Introduction And Aim: Status epilepticus (SE) in children is a critical condition that can be life-threatening. The objective of this study was to identify factors associated with the occurrence of SE after a first convulsive seizure in children.
Methods: A retrospective study was conducted at the pediatric department of BEN AROUS regional hospital between January 2015 and December 2019.
Results: A total of 300 patients admitted for a first epileptic seizure were included in this analysis. The mean age of the patients was 33 months. Seizures were generalized in 92.7%, with tonic-clonic seizures being the most common (54.8%). SE was diagnosed as inaugural in 29% of cases. Abnormalities in EEG were observed in 36.5% of cases, while MRI revealed abnormal results in 32.8% of patients. Factors associated with a risk of SE recurrence were age younger than 1 year (p = 0.003), neuromotor retardation (p = 0.001), EEG abnormalities (p < 0.001), MRI abnormalities (p = 0.001), and abrupte discontinuation of antiepileptic treatment (p < 0.001). Simple febrile seizure was identified as a protective factor (p = 0.038).
Conclusion: The study identified that age under 1 year, neuromotor delay, and abnormalities in EEG and MRI are significant risk factors for the recurrence of status epilepticus after a first epileptic seizure in children. These findings suggest targeted preventive strategies to improve the management and prognosis of these patients.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11668145 | PMC |
| http://dx.doi.org/10.62438/tunismed.v102i11.4493 | DOI Listing |
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