AI Article Synopsis

  • * An 80-year-old woman with cardiac arrest due to a pulmonary embolism was treated successfully using venoarterial ECMO, which stabilized her condition and allowed for the management of subsequent liver and IVC injuries without surgery.
  • * The research indicates that increasing ECMO flow can effectively control bleeding from IVC injuries, suggesting a promising new approach for treating these severe injuries based on both patient outcomes and validation in a dog model.

Article Abstract

Background: Retrohepatic inferior vena cava (IVC) injuries remain among the most lethal and serious liver injuries. Gauze packing is currently the first choice for IVC injuries; however, laparotomy itself poses the risk of circulatory collapse. Thus, less invasive treatment strategies are needed.

Methods: In this study, we conducted an animal experiment to replicate and validate successful treatments for an actual case of retrohepatic IVC injury that we had encountered.

Results: A woman in her 80s presented to our hospital due to cardiac arrest caused by a pulmonary artery embolism. Venoarterial extracorporeal membrane oxygenation (ECMO) was introduced, and the patient was resuscitated. After resuscitation, contrast-enhanced CT revealed liver and retrohepatic IVC injuries, possibly caused by chest compressions. Liver injury was treated using transarterial embolization of the left hepatic artery. To treat the retrohepatic IVC injury, ECMO flow was increased to enhance the negative drainage pressure. The extravasation of the contrast medium had resolved in IVC angiography, and we opted for nonoperative management. The patient's hemodynamic status gradually stabilized, and ECMO was withdrawn on day 6. We confirmed these findings in a dog model of retrohepatic IVC injury.

Conclusions: Our findings from the patient and the animal model suggest that the flow diversion effect of ECMO can effectively manage active bleeding from the IVC by inserting a drainage cannula across the injured lesion. We think this procedure represents a novel treatment option for retrohepatic IVC injuries.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11574402PMC
http://dx.doi.org/10.1136/tsaco-2024-001618DOI Listing

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Article Synopsis
  • * An 80-year-old woman with cardiac arrest due to a pulmonary embolism was treated successfully using venoarterial ECMO, which stabilized her condition and allowed for the management of subsequent liver and IVC injuries without surgery.
  • * The research indicates that increasing ECMO flow can effectively control bleeding from IVC injuries, suggesting a promising new approach for treating these severe injuries based on both patient outcomes and validation in a dog model.
View Article and Find Full Text PDF

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