AI Article Synopsis

  • In the context of rising antibiotic resistance, managing infection sources and timely drainage removal is crucial.
  • A clinical case is discussed involving a 42-year-old patient with various complications, including a urinary stent that led to an infection from pan-resistant Klebsiella pneumonia.
  • The patient's severe condition, including septic shock and coagulation issues, was effectively treated with personalized local bacteriophage therapy.

Article Abstract

In the era of antibiotic resistance, strict control of foci of infection (for example, a long-term stent) and adherence to the timing of drainage removal are necessary. The spread of pan-resistant pathogens requires the development of effective alternative antimicrobial measures, in particular, bacteriophage therapy. A clinical case of a 42-year-old patient with a closed spinal cord injury, lower paraplegia, pelvic organs dysfunction, post-traumatic right ureteral stricture, and right kidney stones is presented in the article. The patient developed stent-associated urosepsis due to pan-resistant Klebsiella pneumonia after endoscopic removal of a long-term right ureteral stent (over 3 months) with endotoxic shock, disseminated intravascular coagulation syndrome and wound sepsis, which was treated using personalized local bacteriophage therapy.

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