AI Article Synopsis

  • Cleft lip and palate (CLP) is a common birth defect that leads to oral function issues and aesthetics concerns, prompting the investigation of maxillary anterior segmental distraction osteogenesis (MASDO) as a corrective treatment.
  • A meta-analysis of 10 studies revealed that MASDO significantly increased maxillary length and improved facial aesthetics, with notable changes in cephalometric measurements.
  • Despite some studies having varying levels of bias, the overall findings support MASDO as a promising therapy for enhancing maxillary structure and function in CLP patients.

Article Abstract

Background: Cleft lip and palate (CLP) is one of the most common birth defects worldwide. It typically results in significant maxillary dysplasia, causing severe oral function problems and substantially affecting the patient's facial aesthetics. Maxillary anterior segmental distraction osteogenesis (MASDO) has gained popularity in recent years as an effective treatment for correcting maxillary dysplasia. However, the evaluation of its effectiveness in patients with CLP varies across different studies. Our research was aimed at providing evidence of the effects of MASDO among CLP patients.

Methods: A meta-analysis covered Medline, Web of Science, Embase, Scopus, and Cochrane Library. Controlled clinical trial studies published before February 2024 and analyzed changes in maxillary cephalometric landmarks before and after MASDO among patients with maxillary hypoplasia and CLP were included.

Results: Our meta-analysis included 10 papers in total. One study was at low risk of bias, seven were at medium risk, and two were at serious risk. MASDO significantly increased the maxillary length. The mean SNA angle increased by 6.43° (95% CI, 4.11° to 8.74°) and A-McNamara rose by 7.29 mm (95% CI, 6.21 mm to 8.37 mm). The maxilla also showed a slight counterclockwise rotation; however, this reached no statistical significance. The mandibular position did not vary remarkably. Moreover, a significant increase in upper anterior tooth tipping and overjet, a decrease in overbite, and an improvement in nasolabial soft tissue were observed.

Conclusions: MASDO might be a valid therapy option for CLP patients. It causes a significant increase in the maxillary length, anterior tooth crossbite, and nasolabial soft tissue were also greatly improved.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11575218PMC
http://dx.doi.org/10.1186/s12903-024-05208-3DOI Listing

Publication Analysis

Top Keywords

maxillary anterior
8
anterior segmental
8
segmental distraction
8
distraction osteogenesis
8
cleft lip
8
lip palate
8
maxillary dysplasia
8
maxillary length
8
anterior tooth
8
nasolabial soft
8

Similar Publications

Automated craniofacial biometry with 3D T2w fetal MRI.

PLOS Digit Health

December 2024

Department of Early Life Imaging, School of Biomedical Engineering and Imaging Sciences, King's College London, St Thomas' Hospital, London, United Kingdom.

Objectives: Evaluating craniofacial phenotype-genotype correlations prenatally is increasingly important; however, it is subjective and challenging with 3D ultrasound. We developed an automated label propagation pipeline using 3D motion- corrected, slice-to-volume reconstructed (SVR) fetal MRI for craniofacial measurements.

Methods: A literature review and expert consensus identified 31 craniofacial biometrics for fetal MRI.

View Article and Find Full Text PDF

Background: The literature has reported contradictory findings regarding the association of Intra-radicular posts (IRPs) presence and periapical radiolucent lesions (PRLs) prevalence in endodontically treated teeth (ETT). Considering this, the study aimed to investigate the association between IRPs presence and PRLs prevalence.

Methods: A cross-sectional study was conducted to compare PRLs prevalence in ETT with and without IRPs.

View Article and Find Full Text PDF

: Orthognathic surgery is used to restore a correct anatomical and functional relationship between the jaws, with postoperative nasal septal deviation (NSD) being a common complication of Le Fort I osteotomy (LF-IO). The aim of this study was to evaluate the occurrence of NSD after LF-IO and to identify possible risk factors. : Pre- and postoperative cone beam computed tomography (CBCT) scans from 2018 to 2023 of 102 patients after LF-IO were analyzed.

View Article and Find Full Text PDF

Background/objectives: Evidence suggests nasal airflow resistance reduces after rapid maxillary expansion (RME). However, the medium-term effects of RME on upper airway (UA) airflow characteristics when normal craniofacial development is considered are still unclear. This retrospective cohort study used computer fluid dynamics (CFD) to evaluate the medium-term changes in the UA airflow (pressure and velocity) after RME in two distinct age-based cohorts.

View Article and Find Full Text PDF

Pulp chamber and root canal obliteration (PCO/RCO) presents a challenge for clinicians when nonsurgical endodontic treatment is indicated. Guided endodontics (GE) aims to precisely locate the root canal (RC) system while preserving as much pericervical dentin as possible. GE involves integrating cone-beam computed tomography (CBCT) of the affected tooth with a digital impression of the maxillary/mandibular arch, allowing for careful planning of the drilling path to the RC system through a three-dimensional (3D) static guide.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!