AI Article Synopsis
- Dental caries is a complex disease driven by diet, host factors, saliva, and dental biofilms, remaining one of the world's most common health issues despite a decline since the 1950s.
- The review highlights the contributions of Henrik Dam, a Nobel Prize winner known for his work on Vitamin K, and how his studies in the mid-20th century explored the effects of Vitamin K, diet, and saliva on dental caries.
- Dam’s research enhanced our understanding of how saliva and various dietary elements, such as fats and proteins, influence the development and prevention of dental caries.
Article Abstract
Dental caries is a multifactorial disease, which is the result of a complex interplay between the diet, the host, the saliva, and dental biofilms. Although the prevalence of dental caries has decreased dramatically since 1950 in many countries, it continues to be one of the most common health conditions globally. The aim of the present review is to summarize the investigations on dental caries performed by the late Noble prize winner Henrik Dam and his colleagues in the middle of the 20th century, and to relate the knowledge and state of the art at the time to current concepts on dental caries. Henrik Dam is mostly known for his discovery of Vitamin K, but he also conducted experimental studies on dental caries that focused on the role of Vitamin K, the diet, and saliva in the development of dental caries. The discoveries of Henrik Dam contributed to our understanding of the role of saliva and different dietary components, such as fat and proteins, in caries development and prevention.
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| http://dx.doi.org/10.1111/apm.13501 | DOI Listing |
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