Introduction And Importance: Low-grade appendicular mucinous neoplasms are rare. In contrast to other malignant tumors, they lack the ability for infiltrative growth or lymph node metastasis, but intraperitoneal mucin spread may lead to a life-threatening condition, known as a pseudomyxoma peritonei.

Case Presentation: Patient, a 47-year-old female, with complaints of a palpable mass in her right inguinal area, presented to our clinic. After a clinical workup, which included computer tomography, magnetic resonance imaging, and colonoscopy, a preliminary diagnosis of LAMN was established. Laparoscopic cecal pole resection was performed. A pathological examination confirmed the diagnosis of LAMN. Patient was followed up for six months after the surgery, at which point a contrast-enhanced CT scan was obtained with no pathological findings.

Clinical Discussion: Mucinous neoplasms of the appendix are a group of tumors in which mucin accumulates within the lumen of the appendix and while this type of neoplasia cannot spread hematologically, extramural mucin may lead to pseudomyxoma peritonei. Not long ago, a right hemicolectomy was accepted as a radical treatment method. Nowadays various studies have shown that laparoscopic appendectomy may be a safe option in patients with mucin, confined to the lumen of the appendix. This case holds educational value due to the detailed course of the disease presented and justified clinical decisions.

Conclusion: LAMN is a rare type of neoplasm. When confined to the lumen of the appendix, it lacks the ability for infiltrative growth and lymph node metastasis. Appropriate treatment in case of a contained disease is surgical removal.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11615890PMC
http://dx.doi.org/10.1016/j.ijscr.2024.110625DOI Listing

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