JGP study (Steinz et al. https://doi.org/10.1085/jgp.202313515) reveals that oxidative stress can induce stable posttranslational modifications of RyR1 that increase the channel's open probability and could therefore disrupt muscle contractility.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11577274 | PMC |
| http://dx.doi.org/10.1085/jgp.202413716 | DOI Listing |
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