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How to undertake and record a 12-lead electrocardiogram.
Nurs Stand
December 2024
Faculty of Science and Technology, Department of Natural Sciences, Middlesex University London, London, England.
Rationale And Key Points: A 12-lead electrocardiogram (ECG) is a painless procedure commonly undertaken in healthcare practice. An ECG machine uses cables or 'leads' attached with stick-on electrodes to specific parts of the body to create a series of ECG traces, which are then printed onto graph paper. This provides a recording of the cardiac electrical activity measured from different angles or perspectives.
View Article and Find Full Text PDFThe Discovery of Autoimmune Nodopathies and the Impact of IgG4 Antibodies in Autoimmune Neurology.
Neurol Neuroimmunol Neuroinflamm
January 2025
Thomas Jefferson University, Philadelphia, PA; and.
In the past decade, significant progress has been made on the understanding of IgG4-mediated autoimmune diseases, of both the central and the peripheral CNS. In addition to the description of diverse antigenic targets, the description of IgG subclasses associated with specific pathogenic autoantibodies has provided useful insights into the pathophysiology and, more importantly, into the therapeutic implications of the autoantibody subclasses. This understanding has affected how myasthenia gravis, autoimmune encephalitis, and autoimmune neuropathies are treated.
View Article and Find Full Text PDFOral Capsule FMT Combined With Bezlotoxumab Is a Successful Rescue Protocol Following Failure of FMT Alone in the Treatment of Recurrent C. difficile Infection.
J Clin Gastroenterol
November 2024
Division of Gastroenterology, Department of Medicine, University of Minnesota, Minneapolis, MN.
Article Synopsis
- The study aimed to assess the effectiveness of adding bezlotoxumab to repeat fecal microbiota transplantation (FMT) for patients with recurrent Clostridioides difficile infections after a previous unsuccessful FMT.
- It was found that combining bezlotoxumab with a second FMT significantly increased the cure rate from 48% to 89%.
- The research highlights the importance of understanding how bezlotoxumab and FMT work together and suggests that similar strategies could apply to other treatments for preventing C. difficile infection recurrence.
Exploring feasibility of fNIRS to assess delayed inhibition effect of prefrontal cortex for acute stress by acupuncture on GV20: a pilot study.
Front Hum Neurosci
November 2024
Department of Acupuncture and Moxibustion, Faculty of Health Care, Teikyo Heisei University, Toshima-ku, Tokyo, Japan.
Introduction: Acupuncture on the acupuncture point GV20 has been considered effective for managing psychoneurological disorders since ancient times, and GV20 is now regularly used to treat stress-related diseases (SRDs), including psychoneurological disorders. Although reports indicating that acupuncture stimulation of GV20 alone regulates cerebral blood flow (CBF) in brain regions associated with SRDs have been scattered, from the perspective of the need for earlier action, the effects on subjective stress as self-reported in the stress state of healthy individuals and CBF changes in related prefrontal cortex (PFC) subregions, which is based as underlying mechanism, remain unclear. Therefore, there is a need to explore effective methods for analyzing such effects.
View Article and Find Full Text PDFRationale to apply specific temperatures for testing NiTi instruments in endodontics-Letter to the authors.
Int Endod J
October 2024
Department of Endodontics, Fluminense Federal University (UFF), Niterói, Brazil.
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