Unilateral virginal hypertrophy of the breast is a rare condition with an unknown etiology, though it is thought to result from hypersensitivity of the end organs to normal levels of gonadal hormones. We present the case of a 17-year-old girl who initially showed gradual growth after thelarche; however, in the last three to four months, there was a rapid increase in size, leading to psychological and physical problems that also impacted her social life. A clinical examination revealed that her left breast was markedly enlarged compared to the right, and she exhibited a drooping posture. Radiological investigations and a true-cut biopsy were performed to detect any underlying pathology, which revealed normocellular stroma consistent with virginal breast hypertrophy.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11570433PMC
http://dx.doi.org/10.7759/cureus.71809DOI Listing

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