Endoscopic Submucosal Resection Turbinoplasty and Partial Inferior Turbinectomy for Management of Inferior Turbinate Hypertrophy: A Randomized Clinical Trial.

Objectives: This study aims to compare outcomes of endoscopic submucosal resection Turbinoplasty and partial inferior turbinectomy in the treatment of Chronic inferior turbinate hypertrophy.

Methods: A randomized prospective comparative study was conducted on 40 patients who complained of a minimum 3-month duration of nasal obstruction combined with clinical findings of moderate to severe inferior turbinate hypertrophy. Patients were divided into two groups: Group A (Endoscopic submucosal resection Turbinoplasty), and Group B (partial inferior turbinectomy) Which included 20 patients in each group. The outcomes of both techniques were analyzed and compared.

Results: A total of 40 patients were randomized with 20 patients assigned to each group. Within each group, there were 12 (60%) females and 8 (40%) males. The median age in Group A was 22.7 (IQR, 7.50), and 26.5 (IQR, 15.5) in Group B. There were statistically significant differences between the two groups regarding nasal obstruction, nasal discharge, and crustations favoring Group A ( < 0.001, 0.003, 0.013 respectively). Additionally, there was a statistically significant increase in anterior nasal space postoperatively in Group A over Group B ( < 0.001) while a statistically significant increase in posterior nasal space was detected in Group B over Group A ( < 0.001). Also, there was a statistically significant reduction in turbinate size anteriorly and posteriorly in Group B over Group A ( < 0.001).

Conclusion: submucosal resection Turbinoplasty is a safe and reliable technique of high efficacy and minimal complications that allows precise excision of hypertrophied stromal tissue in a submucosal plane which protects the physiological function of overlying respiratory precious mucosa and has minimal complications.

Trial Registration: the trial was retrospectively registered at Clinical Trail.Gov identifier: NCT06310083.