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http://dx.doi.org/10.1186/s40779-024-00575-y | DOI Listing |
J Neuroinflammation
November 2024
Department of Neurology, Tangdu Hospital, Air Force Medical University, Xi'an, Shaanxi, 710038, China.
Background: Neuromyelitis optica spectrum disorder (NMOSD) is an autoantibody-triggered central nervous system (CNS) demyelinating disease that primarily affects the spinal cord, optic nerves and brainstem. Among the first responders to CNS injury, microglia are prominent players that drive NMOSD lesion formation. However, the key molecular switches controlling the detrimental activity of microglia in NMOSD are poorly understood.
View Article and Find Full Text PDFMil Med Res
November 2024
Cancer Science Institute of Singapore, National University of Singapore, Singapore, 117599, Singapore.
Arthritis Res Ther
November 2024
GenNBio Inc, 80, Deurimsandan 2-ro, Cheongbuk-eup, Pyeongtaek-si, Gyeonggi-do, 17796, Republic of Korea.
Kidney Res Clin Pract
September 2024
Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Republic of Korea.
Background: Membranous nephropathy (MN) is a specific autoimmune disease affecting kidneys. It is characterized by the accumulation of immune complexes in the glomerular basement membrane. Renal biopsy is currently the standard procedure to confirm the diagnosis, although the presence of autoantibodies against the phospholipase A2 receptor (PLA2R) can also help diagnose.
View Article and Find Full Text PDFCurr Oncol
August 2024
Medical Informatics Laboratory, Yaroslav-the-Wise Novgorod State University, 173003 Veliky Novgorod, Russia.
Invasion and metastasis are important hallmarks of lung cancer, and affect patients' survival. Early diagnostics of metastatic potential are important for treatment management. Recent findings suggest that the transition to an invasive phenotype causes changes in the expression of 700-800 genes.
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