Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1136/bmj.q2416 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Crosstalk Between Oxidative Stress and Epigenetics: Unveiling New Biomarkers in Human Infertility.
Cells
November 2024
Department of Life Science and Bioinformatics, Assam University, Silchar 788011, India.
The correlation between epigenetic alterations and the pathophysiology of human infertility is progressively being elucidated with the discovery of an increasing number of target genes that exhibit altered expression patterns linked to reproductive abnormalities. Several genes and molecules are emerging as important for the future management of human infertility. In men, microRNAs (miRNAs) like miR-34c, miR-34b, and miR-122 regulate apoptosis, sperm production, and germ cell survival, while other factors, such as miR-449 and sirtuin 1 (SIRT1), influence testicular health, oxidative stress, and mitochondrial function.
View Article and Find Full Text PDFSingle-cell transcriptomic analysis of endometriosis.
Nat Genet
February 2023
Women's Cancer Research Program at the Samuel Oschin Comprehensive Cancer Center, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
Article Synopsis
- Endometriosis is a painful condition in women that can cause problems with getting pregnant and may increase the risk of ovarian cancer.
- Researchers studied over 370,000 cells from different tissue types related to endometriosis and found that cells behaved differently depending on where they came from.
- They discovered that certain changes in the cells and their functions could play a role in the disease itself and its connection to ovarian cancers.
Internet-based cognitive behavioral therapy for improving health-related quality of life in patients with endometriosis: study protocol for a randomized controlled trial.
Trials
April 2022
Dept. of Psychology, Division of Clinical Psychology and Psychotherapy, Philipps-University Marburg, Marburg, Germany.
Background: The trial investigates the efficacy of internet-based cognitive behavioral therapy (iCBT) in improving health-related QoL in patients with endometriosis, which is a chronic gynecological condition affecting up to 15% of people with female-assigned reproductive organs. Endometriosis is stress-related and comes with various physical symptoms such as pelvic pain and infertility. It has a substantial impact on health-related quality of life (QoL), and mind-body interventions seem promising in reducing the psychological burden.
View Article and Find Full Text PDFIn this study, we examined whether beliefs regarding motherhood, female identity, and infertility affected the psychological health of 127 childless endometriosis patients. Anxiety and depression were measured using the Hospital Anxiety and Depression Scale, while self-esteem was assessed using the Rosenberg Self-Esteem Scale. A set of six Likert-type items (1 = "Not at all"; 5 = "To a very great extent") was developed to explore women's beliefs.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!