Objective: Various studies have failed to detect a difference in outcomes between carotid endarterectomy (CEA) with patch angioplasty and eversion CEA. This study aimed to assess whether surgical technique and related department policy are associated with in hospital outcomes after CEA.
Methods: This was a secondary data analysis based on the German statutory quality assurance database. According to surgical technique policy, hospitals were categorised as routine eversion (> 90%), selective eversion (10 - 90%), or sporadic eversion (< 10%) centres. The primary outcome event (POE) was in hospital stroke or death. Uni- and multivariable regression analyses were performed.
Results: A total of 119 800 patients underwent CEA between 2012 and 2016. Multivariable regression analysis showed the eversion technique to be associated with a lower POE rate (adjusted odds ratio 0.78, 95% confidence interval 0.69 - 0.88). Routine eversion centres showed statistically significantly lower in hospital stroke or death rates compared with selective eversion and sporadic eversion centres (1.7% vs. 1.9% vs. 2.0%; p = .004). After risk adjustment, centre surgical technique policy did not show a significant association with any of the assessed outcomes.
Conclusion: Eversion CEA compared with CEA with patch angioplasty was independently associated with a lower in hospital stroke or death rate. The centre policy with respect to surgical technique did not show an association with the primary or either of the secondary outcomes.
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http://dx.doi.org/10.1016/j.ejvs.2024.11.016 | DOI Listing |
Cardiovasc Diabetol
January 2025
State Key Laboratory of Systems Medicine for Cancer, Center for Single-Cell Omics, School of Public Health, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Background: Among hypertensive cohorts across different nations, the relationship between the triglyceride-glucose index (TyG) and its conjunction with obesity metrics in relation to cardiovascular disease (CVD) incidence and mortality remains to be elucidated.
Methods: This study enrolled 9,283, 164,357, and 5,334 hypertensives from the National Health and Nutrition Examination Survey (NHANES), UK Biobank (UKBB), and Shanghai Pudong cohort. The related outcomes for CVD were defined by multivariate Cox proportional hazards models, Generalized Additive Models and Mendelian randomization analysis.
Sci Rep
January 2025
School of Computer Science and Engineering, VIT-AP University, Vijayawada, India.
In recent years, the healthcare data system has expanded rapidly, allowing for the identification of important health trends and facilitating targeted preventative care. Heart disease remains a leading cause of death in developed countries, often leading to consequential outcomes such as dementia, which can be mitigated through early detection and treatment of cardiovascular issues. Continued research into preventing strokes and heart attacks is crucial.
View Article and Find Full Text PDFJACC Cardiovasc Imaging
January 2025
Division of Vascular Surgery, Stanford University Medical Center, Stanford, California, USA. Electronic address:
Br J Gen Pract
January 2025
University of Oxford Department of Primary Care Health Sciences, Oxford, United Kingdom.
Background: Heart failure (HF) is a risk factor for stroke among people with atrial fibrillation (AF). Prognosis following a HF diagnosis is often poor, but this is not accounted for in existing stroke risk scores.
Aim: To examine stroke incidence in people with HF and AF compared to AF alone, considering the competing risk of death.
Am J Cardiol
January 2025
Cardiology Division, Massachusetts General Hospital, Boston, MA, USA; Harvard Medical School, Boston, MA, USA; Baim Institute for Clinical Research, Boston, MA, USA. Electronic address:
There are limited tools available to predict the long-term prognosis of persons with coronary chronic total occlusions (CTO). A previously-described blood biomarker panel to predict cardiovascular (CV) events was evaluated in patients with CTO. From 1251 patients in the CASABLANCA study, 241 participants with a CTO were followed for an average of 4 years for occurrence of major adverse CV events (MACE, CV death, non-fatal myocardial infarction or stroke) and CV death/heart failure (HF) hospitalization.
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