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CT-guided Left Stellate Ganglion Cryoneurolysis for Refractory Ventricular Arrhythmias.
Radiology
December 2024
From the Department of Radiology, Division of Interventional Radiology (N.L., N.J.R.), Department of Medicine, Division of Interventional Cardiology (Y.R.), and Department of Medicine, Division of Cardiovascular Medicine (Y.R., G.S., M.G.), UMass Memorial Medical Center and Chan Medical School, 55 Lake Ave N, S2-817A, Worcester, MA 01655; Department of Radiology and Imaging Sciences, Division of Interventional Radiology and Image-Guided Medicine, Emory University School of Medicine, Atlanta, Ga (J.K.); Division of Cardiology, Division of Electrophysiology, Emory Heart & Vascular Center at Saint Joseph's Hospital, Atlanta, Ga (A.M.P., C.M.T.); Department of Heart Failure/Transplant Cardiology, Piedmont Heart Institute, Piedmont Healthcare, Atlanta, Ga (D.W.M.); and Franklin College of Arts and Sciences, University of Georgia, Athens, Ga (F.J.P.).
Background Ventricular arrhythmias (VAs), including ventricular tachycardia and ventricular fibrillation, present substantial therapeutic challenges due to their high morbidity, mortality, and increasing prevalence. Current treatments often prove infeasible or inadequate in patients with refractory VAs. Purpose To evaluate the safety and effectiveness of CT-guided left stellate ganglion cryoneurolysis (SGC) in the treatment of refractory VAs.
View Article and Find Full Text PDFStereotactic arrhythmia radioablation for ventricular tachycardia: a review of clinical trials and emerging roles of imaging.
J Radiat Res
December 2024
Department of Radiology, Nagoya University Graduate School of Medicine, 65 Tsurumaicho, Showa-ku, Nagoya, Aichi, 466-8550, Japan.
Ventricular tachycardia (VT) is a severe arrhythmia commonly treated with implantable cardioverter defibrillators, antiarrhythmic drugs and catheter ablation (CA). Although CA is effective in reducing recurrent VT, its impact on survival remains uncertain, especially in patients with extensive scarring. Stereotactic arrhythmia radioablation (STAR) has emerged as a novel treatment for VT in patients unresponsive to CA, leveraging techniques from stereotactic body radiation therapy used in cancer treatments.
View Article and Find Full Text PDFComplexities of Management of Atypical Ventricular Fibrillation Storm in a Young Patient With TANGO2.
Case Rep Pediatr
December 2024
Paediatric Cardiac Anaesthetic Department, Bristol Royal Hospital for Children, Upper Maudlin Street, Bristol BS2 8BJ, UK.
TANGO2 deficiency disorder, a rare autosomal recessive genetic disorder characterised by biallelic loss-of-function variants in the TANGO2 gene, was first described in 2016. This disorder involves the transport and Golgi organisation homologue, impacting Golgi membrane redistribution into the endoplasmic reticulum. Clinically, affected individuals exhibit a multiorgan phenotype, with prominent neurological manifestations such as developmental delay and regression.
View Article and Find Full Text PDFExploring Cardiac Sympathetic Denervation as a Treatment Approach for Recurrent Ventricular Arrhythmias: A Concise Review.
J Clin Exp Cardiolog
March 2024
Division of Thoracic Surgery, Johns Hopkins University School of Medicine, Baltimore, USA.
Article Synopsis
- * Bilateral CSD (BCSD) shows an approximate 60% reduction in implantable cardioverter defibrillator shocks and over 50% one-year survival without shock or transplant, while the 2017 guidelines endorse the left CSD for specific RVT types.
- * Despite the promising results, many studies have small sample sizes leading to potential underreporting of complications; more research is needed to fully understand the long
Long-term results of stereotactic arrhythmia radioablation for refractory ventricular Arrhythmias-A Taiwanese population study.
J Formos Med Assoc
December 2024
Division of Cardiology, Department of Internal Medicine, National Taiwan University College of Medicine and Hospital, Taipei, Taiwan; Cardiovascular center, National Taiwan University College of Medicine and Hospital, Taipei, Taiwan. Electronic address:
Article Synopsis
- Stereotactic arrhythmia radioablation (STAR) has shown effectiveness for treating refractory ventricular tachyarrhythmia (VT), with a focus on a Taiwanese patient group.
- The study involved 11 patients, using advanced imaging techniques to treat VT with a single radiation dose, resulting in a significant 88% reduction in VT episodes within the first six months post-treatment.
- Despite initial success, many patients experienced late VT recurrence, with a one-year survival rate of 83%, leading to some requiring additional treatments such as heart transplants or HeartMate III implantation.
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