Objective: To describe the clinical presentation and diagnosis of bilateral diaphragmatic paralysis in a weanling miniature donkey jack.
Case Summary: A 5-month-old miniature donkey jack presented to a tertiary care facility for fever, cough, and increased respiratory rate and effort initially unresponsive to treatment with antimicrobials and anti-inflammatories. Clinical and diagnostic evaluations found no evidence of upper respiratory obstruction or bacterial pneumonia. Serial arterial blood gas evaluations revealed hypercapnia and hypoxemia, and diagnostic imaging was consistent with bilateral diaphragmatic paralysis. The patient's nasal swab for equine influenza type A (subtype H3N8) was positive and had a mildly decreased whole blood selenium concentration. The donkey recovered after treatment with anti-inflammatories and supportive care.
New Or Unique Information Provided: This case documents the first report of diaphragmatic paralysis in a donkey, with concurrent equine influenza infection offering a possible causal factor. Bilateral diaphragmatic paralysis should be considered as a differential diagnosis for respiratory distress in donkeys, particularly when diagnostic testing or treatment trials do not support more common causes of respiratory disease in adult animals, such as infectious lower airway disease, asthma, and pulmonary fibrosis.
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http://dx.doi.org/10.1111/vec.13424 | DOI Listing |
Neurooncol Adv
December 2024
Center for Translational Immunology, University Medical Center Utrecht, Utrecht, The Netherlands.
Background: Intrathecal (IT) chemotherapy is essential in treating hematological malignancies, but it can lead to ascending paraplegia, a condition that currently lacks clear management guidelines.
Methods: We conducted a systematic review, analyzing 1219 studies and 116 patients, adhering to PRISMA guidelines for individual patient data. The study, registered under PROSPERO (CRD42022362121), focused on the onset, diagnostic approaches, and therapeutic interventions associated with this complication, and management strategies to tackle the ascending paraplegia.
Ann Thorac Surg Short Rep
September 2024
Department of General Thoracic Surgery, Juntendo University School of Medicine, Tokyo, Japan.
Dynamic chest radiography (DCR) is a novel radiographic technique that evaluates the thoracic movement from inspiration to expiration. Here, we report the efficacy of DCR in the surgical treatment of diaphragmatic paralysis. A 60-year-old woman presented with phrenic nerve palsy after anterior mediastinal resection.
View Article and Find Full Text PDFJ Clin Med
December 2024
Department of Surgery, Tohoku University Graduate School of Medicine, 2-1 Seiryo-machi, Aoba-ku, Sendai 980-8575, Miyagi, Japan.
Recurrent laryngeal nerve palsy remains a significant complication following minimally invasive esophagectomy for esophageal cancer. Despite advancements in surgical techniques and lymphadenectomy precision, the incidence of recurrent laryngeal nerve palsy has not been improved. Recurrent laryngeal nerve palsy predominantly affects the left side and may lead to unilateral or bilateral vocal cord paralysis, resulting in hoarseness, dysphagia, and an increased risk of aspiration pneumonia.
View Article and Find Full Text PDFClin Med Insights Case Rep
January 2025
Department of Rehabilitation, Nara Prefectural General Medical Center, Nara, Japan.
Background: Spasticity is an upper motor neuron syndrome that exacerbates motor paralysis and is rarely associated with pain. This report elucidates the management of drug-resistant pain attributed to an adolescent brain tumor using botulinum therapy.
Case Presentation: A 15-year-old female patient experienced dizziness, developed muscle weakness in her upper extremities, and was diagnosed with diffuse glioblastoma of the pons.
Sci Rep
January 2025
Department of Anesthesiology, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, No.600 Yishan Road, Xuhui District, Shanghai, 200233, People's Republic of China.
Regional anesthesia is a popular method for surgical anesthesia in clavicular surgery. Selective blocking of the cervical 3, 4, and 5 nerve roots shows promise in clavicle surgery, with its fast onset, good anesthesia and less complications, necessitating evaluation of its impact on diaphragmatic function. The purpose of this study is to examine the safety of C3, 4, and 5 nerve root block for its application in clavicle surgery.
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