Line spectrum tracking is an essential signal-processing method for underwater passive detection. However, its performance is often seriously degraded due to signal fluctuation, especially in low signal-to-noise ratio scenarios. In this paper, based on signal space transformation and hidden Markov model, a signal trajectory tracking method is proposed for underwater moving target detection and parameter estimation. With this method, tracking the varying line spectrum trajectory in three-dimensional frequency-azimuth-time signal space is constrained onto a two-dimensional plane in the transformed signal space. Not only is the computation complexity reduced, but the ability to track weak line spectrums and estimate target parameters is improved. The performance of this method is verified with numerical simulations and experimental data processing.
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ACS Cent Sci
December 2024
School of Chemistry and Chemical Engineering, New Cornerstone Science Laboratory, Frontiers Science Center for Transformative Molecules, National Center for Translational Medicine, Shanghai Jiao Tong University, Shanghai, 200240, China.
DNA computing leverages molecular reactions to achieve diverse information processing functions. Recently developed DNA origami registers, which could be integrated with DNA computing circuits, allow signal transmission between these circuits, enabling DNA circuits to perform complex tasks in a sequential manner, thereby enhancing the programming space and compatibility with various biomolecules of DNA computing. However, these registers support only single-write operations, and the signal transfer involves cumbersome and time-consuming register movements, limiting the speed of sequential computing.
View Article and Find Full Text PDFNeural Netw
December 2024
Department of Artificial Intelligence, Korea University, South Korea. Electronic address:
Moiré patterns, created by the interference between overlapping grid patterns in the pixel space, degrade the visual quality of images and videos. Therefore, removing such patterns (demoiréing) is crucial, yet remains a challenge due to their complexities in sizes and distortions. Conventional methods mainly tackle this task by only exploiting the spatial domain of the input images, limiting their capabilities in removing large-scale moiré patterns.
View Article and Find Full Text PDFEur J Pharm Sci
December 2024
Institute of Pharmaceutical Sciences, University of Freiburg, 79104 Freiburg im Breisgau, Germany; Andreas Hettich GmbH & Co. KG, 78532 Tuttlingen, Germany.
Thermosensitive liposomes (TSLs) have great potential for the selective delivery of cytostatic drugs to the tumor site with greatly reduced side effects. Here we report the discovery and characterization of new thermosensitive small multilamellar lipid nanoparticles (tSMLPs) with unusually high temperature selectivity. Furthermore, the temperature-dependent release of the fluorescent marker calcein from tSMLPs is enhanced by human serum albumin.
View Article and Find Full Text PDFMAGMA
December 2024
Department of Radiology and Medical Informatics, Faculty of Medicine, University of Geneva, Geneva, Switzerland.
Objectives: Phosphorus-31 magnetic resonance spectroscopic imaging (P-MRSI) is a non-invasive tool for assessing cellular high-energy metabolism in-vivo. However, its acquisition suffers from a low sensitivity, which necessitates large voxel sizes or multiple averages to achieve an acceptable signal-to-noise ratio (SNR), resulting in long scan times.
Materials And Methods: To overcome these limitations, we propose an acquisition and reconstruction scheme for FID-MRSI sequences.
mBio
December 2024
Department of Microbiology, Heersink School of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, USA.
Bacteria encounter numerous stressors in their constantly changing environments and have evolved many methods to deal with stressors quickly and effectively. One well-known and broadly conserved stress response in bacteria is the stringent response, mediated by the alarmone (p)ppGpp. (p)ppGpp is produced in response to amino acid starvation and other nutrient limitations and stresses and regulates both the activity of proteins and expression of genes.
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