AI Article Synopsis
- The study aimed to evaluate embryo transfer strategies for patients with low oocyte retrieval (3 or fewer oocytes) undergoing IVF and FET from January 2018 to December 2022.
- Researchers analyzed data from 202 fresh IVF cycles and 87 frozen embryo transfer cycles, comparing various patient and treatment characteristics to assess clinical pregnancy outcomes.
- Findings indicated that younger patients (under 35) should have all embryos frozen for later transfer, while those 35 and older can benefit from fresh transfers to reduce costs and treatment frequency without lowering pregnancy rates.
Article Abstract
Objective: To explore the choice of embryo transfer schemes for patients with low oocyte retrieval (≤ 3 oocytes).
Methods: A retrospective analysis was conducted on patients with oocyte yields ≤ 3 undergoing in vitro fertilization and embryo transfer (IVF-ET) and frozen embryo transfer (FET) at the Maternity & Child Care Center of Qinhuangdao Reproductive Medicine Department from January 2018 to December 2022. The data included 202 fresh cycles, with 104 cycles in Group-A and 98 cycles in Group-B. Additionally, 87 cycles involved the transfer of frozen embryos from fresh cycles that could not be transplanted for various reasons, with 31 cycles in Group-C and 56 cycles in Group-D. General patient information, embryo transfer details, and clinical pregnancy outcomes in both fresh and frozen cycles were statistically analyzed.
Results: No significant differences were observed between Groups A and C in age, anti-Müllerian hormone (AMH), basal follicle-stimulating hormone (bFSH), body mass index (BMI), duration of infertility, the proportion of patients with diminished ovarian reserve (DOR), oocyte retrieval count, usable embryo count, or the number of transplanted embryos (all p> 0.05). Advanced age was a risk factor for a decreased pregnancy rate, and FET significantly increased the pregnancy rate (p< 0.05, respectively).
Conclusion: For patients under 35 years old with low oocyte retrieval, it is recommended to freeze all embryos when available and then proceed with FET. For patients aged 35 and above, without reducing the pregnancy rate, fresh embryo transfer is recommended to minimize treatment cycle frequency and economic expenses.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11568712 | PMC |
| http://dx.doi.org/10.12669/pjms.40.10.9269 | DOI Listing |
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