Background: Viruses cause various human diseases, some of which become pandemic outbreaks lack effective treatments and vaccines. This study gathered data on Carica papaya's antiviral effects against various human viruses, highlighting its potential as a natural treatment. Through , , and clinical study analysis, we illustrated the potential of Carica papaya in combating viral infections and its potential role in cure of common viral diseases.
Method: ology: Research papers on antiviral activity of Carica papaya were identified by using specific keywords in PUBMED, Google Scholar, and ScienceDirect databases. Articles published between January 2015 and March 2024 were screened for inclusion. Eligible studies utilized Carica papaya leaves (powder or juice) or fruits to investigate their effects against human viral infections. Each selected study applied either qualitative or quantitative antiviral assays to assess the efficacy of Carica papaya in combating human viruses.
Results: Fifteen studies went through assessment for antiviral properties of Carica papaya, 7 (46.67 %) of them displayed significant activity against the dengue virus, while 1 study (6.67 %) demonstrated moderate/less effectiveness against dengue serotype-2. Two studies (13.33 %) found no anti-dengue effects. Additionally, Carica papaya exhibited strong antiviral activity against SARS-CoV-2 in 2 studies (13.33 %). One study (6.67 %) showed inhibition of both dengue serotype-2 and chikungunya, and 1 study (6.67 %) each demonstrated inhibitory effects against human immunodeficiency virus and Zika virus infections.
Conclusion: The present study listed human diseases for which Carica papaya revealed significant antiviral effects against Dengue virus, Severe acute respiratory syndrome, Human immunodeficiency virus-I, Chikungunya virus and Zika virus suggesting its potential as a treatment candidate for all these viruses. However, the majority of the research involved screening, with minimal and clinical testing. Further studies and clinical trials should be conducted to explore the potential of Carica papaya in the treatment of human viral infections.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11566848 | PMC |
| http://dx.doi.org/10.1016/j.heliyon.2024.e39635 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Effects of dietary garlic () and papaya () leaf powder on production performance, ruminal methanogen levels, gut parameters, and meat quality in goats.
Vet World
November 2024
Department of Physiology, University of Veterinary and Animal Sciences, 54000, Lahore, Pakistan.
Background And Aim: Several approaches have been employed to mitigate methane emissions from livestock, with varied results. This study evaluated the effects of shade-dried ground garlic leaf (GL) powder and papaya leaf (PL) powder as crop waste on feed intake, growth performance, ruminal microbial counts, gut epithelial barrier functions, and meat quality in goats.
Materials And Methods: Forty male adult Beetal goats were randomly divided into five treatment groups: (1) Control (basal diet only); (2) basal diet supplemented with 6% bromodichloromethane (BCM); (3) basal diet supplemented with 30% GL powder; (4) basal diet supplemented with 26% PL powder; and (5) basal diet supplemented with 30% GL powder and 26% PL powder (GP).
The effect of combined fig-Walnut syrup on functional constipation in pregnant women: a randomized controlled trial.
Nutr Metab (Lond)
January 2025
Social Determinants of Health Research Center, Faculty of Nursing and Midwifery, Tabriz University of Medical Sciences, Tabriz, Iran.
Background: Constipation is one of the most common gastrointestinal complaints during pregnancy. Consuming fruits and vegetables is often the first line of treatment due to their fiber content. Therefore, the purpose of the present study was to determine the effect of combined fig-walnut syrup on functional constipation (FC) and quality of life (QoL) in pregnant women.
View Article and Find Full Text PDFDetermination of optimal gamma radiation dose for mutation breeding in 'Sabz' fig (Ficus carica L.) cuttings based on radiosensitivity and phenotypic changes.
PLoS One
January 2025
Fig Research Station, Fars Agricultural and Natural Resources Research and Education Center, Agricultural Research, Education and Extension Organization (AREEO), Estahban, Iran.
The dried fig cv. Sabz of Iran, distinguishes out among the several fig cultivars for its unique characteristics and excellent properties. The aims to this study were 1) Carefully monitoring the resulting phenotypic changes in growth patterns, leaf morphology, shoot traits, root characteristics, and other relevant traits after irradiated with different gamma rays; 2) Investigating the LD25, 50, 75 and GR25, 50, 75 values at different gamma radiation doses for chose optimum dose.
View Article and Find Full Text PDFFruit quality retention and shelf-life extension of papaya through organic coating.
Heliyon
January 2025
Department of Horticulture, Bangabandhu Sheikh Mujibur Rahman Agricultural University, Gazipur, 1706, Bangladesh.
Papaya ( L.) is a climacteric fruit which lose quality and shelf life quickly due to physiological decay and microbial infection after harvest. The study was conducted to evaluate newly applied clybio formulation (0.
View Article and Find Full Text PDFEvaluation of the anti-cholelithiasis activity of vinegar-soaked Ficus carica fruit in adults: A randomized controlled trial.
Pak J Pharm Sci
January 2025
Department of Pathobiology and Biomedical Sciences, Muhammad Nawaz Sharif University of Agriculture, Multan, Pakistan/Ali-Ul-Murtaza Department of Rehabilitation Sciences, Muhammad Institute of Medical and Allied Sciences, Multan, Pakistan.
This study aimed to evaluate the efficacy of vinegar-soaked Ficus carica fruits (VSFCF) for managing cholelithiasis in adults. A parallel-group, single-blinded, randomized controlled trial at Noreen Nishat Welfare Hospital, Khanewal, Pakistan, was conducted from December 2023 to February 2024. Fifty adults with ultrasound-confirmed cholelithiasis were randomly assigned to receive either VSFCF (1 g/kg/day) or ursodiol (600 mg/day).
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!