AI Article Synopsis

  • Penile amputation is a rare but serious urological emergency that can result from various factors, necessitating advanced microsurgical techniques for successful reattachment to restore function and appearance.
  • *Recent advancements in microsurgery have improved the outcomes of penile replantation by allowing precise reconnections of blood vessels and nerves, which are essential for maintaining erectile function and sensation.
  • *A review of 46 cases identified common complications like postoperative necrosis (56.5%) and emphasized the importance of quick vascular repairs, while also suggesting new treatments such as hyperbaric oxygen therapy and the need for standardized protocols to improve outcomes and patient quality of life.

Article Abstract

Penile amputation is a rare urological emergency with varying etiologies, ranging from psychiatric disorders to traumatic injuries, and requires precise microsurgical replantation techniques to restore function and appearance. The popularization of microsurgery has greatly improved outcomes by enabling accurate vascular and nerve reattachments, which are crucial for erectile function and sensation. This comprehensive study reviews advancements in microsurgical penile replantation, perioperative, and postoperative care, focusing on the nuances of surgical interventions and potential complications such as ischemia and necrosis. The PubMed, EMBASE, and Cochrane databases, were queried for studies published between 2015 and 2023 that discussed preoperative conditions, surgical techniques, and postoperative outcomes in penile replantation cases. Resulting studies that reported preoperative and postoperative outcomes of at least one case of penile replantation after amputation were included. Case parameters of interest were then extracted and categorized to determine the most common complications as well as solutions utilized in penile replantation. Our findings from 46 cases across 37 studies revealed a common occurrence of postoperative necrosis (56.5%) and highlighted the importance of timely vascular reconnection and innovative surgical strategies to manage complications. Three cases were complicated by scrotal hematomas and 23 cases reported at least one psychiatric comorbidity. Some innovative solutions mentioned include hyperbaric oxygen therapy, laser angiography, leech therapy, PDE inhibitors, and penile splints. The outcomes suggest a critical need for standardized protocols and further research into optimizing techniques and therapies to enhance the success rates as well as quality of life post-replantation. This review aims to guide future practices and encourage collaborative efforts to refine the complex microsurgical procedures involved in penile replantation.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11562141PMC
http://dx.doi.org/10.1177/22925503241265299DOI Listing

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Article Synopsis
  • Penile amputation is a rare but serious urological emergency that can result from various factors, necessitating advanced microsurgical techniques for successful reattachment to restore function and appearance.
  • *Recent advancements in microsurgery have improved the outcomes of penile replantation by allowing precise reconnections of blood vessels and nerves, which are essential for maintaining erectile function and sensation.
  • *A review of 46 cases identified common complications like postoperative necrosis (56.5%) and emphasized the importance of quick vascular repairs, while also suggesting new treatments such as hyperbaric oxygen therapy and the need for standardized protocols to improve outcomes and patient quality of life.
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A Guide to the Implementation and Design of Ex Vivo Perfusion Machines for Vascularized Composite Allotransplantation.

Plast Reconstr Surg Glob Open

November 2024

From the Department of Plastic and Reconstructive Surgery, Vascularized Composite Allotransplantation Laboratory, Johns Hopkins University School of Medicine, Baltimore, Md.

Background: Ex vivo machine perfusion (EVMP) is a versatile platform utilized in vascularized composite allotransplantation (VCA) to prolong preservation, salvage tissue, and evaluate graft viability. However, there is no consensus on best practices for VCA. This article discusses the common components, modifications, and considerations necessary for a successful VCA perfusion.

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Introduction: To date, there are only case reports of penile amputation, a rare urological emergency with a low-treatment successful rate, and there are still no advanced, detailed surgical or perioperative treatment plans. Effective treatments for these rare diseases are urgently needed.

Method: The researchers summarized the perioperative experience of 20 patients who underwent replantation after complete penile amputation at several hospitals over the past 5 years and shared experience in detail.

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Introduction And Importance: Genital self-mutilation is a rare urologic surgical emergency that is usually encountered in patients with underlying psychiatric illness. Because of shortage of published data and variance in management schemes worldwide, these conditions can present a significant management dilemma.

Case Presentation: In this case report we present this rare phenomenon, where a known schizophrenic patient presented after he amputated both of his testes and penis under the influence of command hallucination.

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A microsurgical approach to post-traumatic penile amputation: Towards standardizing the technique - A case report.

Int J Surg Case Rep

March 2024

Department of Urology, Souss Massa University Hospital, Faculty of Medicine and Pharmacy of Agadir, Ibn Zohr University, Agadir, Morocco. Electronic address:

Introduction: Penile amputation is an unusual situation reported globally as isolated cases and small series. It constitutes a urological emergency which requires microsurgical skills for the repair of the penis. We present a case of a penile amputation and discuss the management of this challenging condition.

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