Message: file_get_contents(https://...@gmail.com&api_key=61f08fa0b96a73de8c900d749fcb997acc09): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests
Unveiling the Masked Culprit: Central Nervous System Infection With Varicella-Zoster Virus Diagnosed by Multiplex PCR in an Elderly Patient With Atypical Neurological Symptoms. | LitMetric
* Using cerebrospinal fluid multiplex polymerase chain reaction (PCR) testing, doctors quickly identified VZV, leading to immediate antiviral treatment.
* This situation emphasizes the need to think about VZV in rare neurological cases and showcases how multiplex PCR can improve diagnosis, especially in cases without common symptoms.
Article Abstract
Varicella-zoster virus (VZV) infections of the central nervous system can be atypical, particularly in elderly patients. Herein, we describe the case of an 80-year-old male presenting with persistent hiccups and dysphagia without the characteristic rash typically associated with VZV infection. Cerebrospinal fluid multiplex polymerase chain reaction (PCR) allowed rapid identification of VZV, thereby enabling the prompt initiation of antiviral therapy. This case underscores the importance of considering VZV in atypical neurological presentations and highlights the utility of multiplex PCR in diagnosing zoster sine herpes, potentially altering the diagnostic approach for similar cases.
