Spontaneous Resolution of Post-COVID-19-Associated Sacral Neuromodulation Device Dysfunction and Overactive Bladder Symptoms: A Report of Two Cases.

Sacral neuromodulation (SNM) is an effective third-line therapy for overactive bladder (OAB). COVID-19 may have a temporary negative effect on SNM function. We describe two cases of increased sensory thresholds and loss of SNM efficacy following COVID-19 infection. In both of these cases, SNM efficacy, sensory thresholds, and impedances were spontaneously restored after a few months without surgical intervention. Withholding surgical revision due to transient post-COVID-19-induced SNM impairment may be appropriate; however, further research is needed to elucidate the mechanism involved with COVID-19 interaction with SNM functionality.