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George Gomori's Contributions to Diabetes Research and the Origins of the . | LitMetric

George Gomori's Contributions to Diabetes Research and the Origins of the .

J Histochem Cytochem

Division of Metabolism, Endocrinology, and Nutrition, Department of Medicine, University of Washington, Seattle, Washington (DGB).

Published: December 2024

AI Article Synopsis

  • Gomori was a key figure in enzyme histochemistry for nearly 30 years, pioneering methods to demonstrate enzyme activity, especially phosphatases, esterases, and lipases.
  • He made significant strides in diabetes research by creating histological techniques that effectively stained insulin-secreting B cells in the pancreas, which were crucial for understanding the disease.
  • As a founding member and President of The Histochemical Society, Gomori played a pivotal role in advancing the field, including serving as one of the first Associate Editors for the society's journal.

Article Abstract

Over a period of almost 30 years, Gomori was one of the most prolific and productive investigators in the emerging field of enzyme histochemistry and was recognized by his peers as a pioneer in developing methods for the histochemical demonstration of hydrolytic enzyme activity, most notably phosphatases, esterases, and lipases. Gomori also made important contributions to diabetes research by developing histological techniques that reliably stained the insulin-secreting B cell of the pancreatic islets of Langerhans. Gomori's aldehyde fuchsin staining method was standard for pathological and physiological studies on islet B cells in relation to diabetes and obesity until insulin antibodies became widely available for immunohistochemical identification of B cells. Gomori was a founding member of The Histochemical Society in 1950. When the HCS established the in 1953, Gomori served as one of the first Associate Editors. He also served as President of The Histochemical Society.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11572951PMC
http://dx.doi.org/10.1369/00221554241300370DOI Listing

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