Background: In this prospective study, we evaluated whether a sufficient number of glomeruli were achieved using the 8× magnification of smartphone cameras.
Purpose: To increase the percutaneous ultrasound-guided renal biopsy (PURB) diagnostic value with a method that has not been tried before and reduce the need for repetition of the procedure.
Material And Methods: A total of 39 adult patients who underwent PURB were included in our study. After the PURB was applied to the patients, the biopsy specimen was placed on the previously prepared sterile gauze. At this stage, 8× magnification photos were taken of the biopsy samples using the smartphone camera. The glomeruli in the photograph were counted and recorded and compared with the number of glomeruli seen at the end of the histopathological examination.
Results: The mean number of glomeruli in the evaluated samples was counted as 6 ± 2.2 (range = 1-10) in the 8× magnification photograph. The mean number of glomeruli detected in the histopathological examination of these samples was 11 ± 5.7 (range = 2-30). A pathological glomeruli count of 10 was associated with more than five brown spots in the 8× magnification photograph (area under the curve = 0.977, =0.0001).
Conclusion: To obtain more than 10 glomeruli in a PURB specimen, five or more brownish-red dots should be counted on the 8x magnification photograph. Using smartphones as an alternative tool for evaluating renal biopsy tissue adequacy can be practical and advantageous in terms of time and labor.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1177/02841851241295393 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Sex differences in olfactory behavior and neurophysiology in Long Evans Rats.
J Neurophysiol
December 2024
Institute for Mind and Biology, The University of Chicago, Chicago, IL 60637.
In many species, olfactory abilities in females are more acute than those in males. Studies in humans show that women have lower olfactory thresholds and are better able to discriminate and identify odors than men. In mice, odorants elicit faster activation from a larger number of olfactory bulb glomeruli in females than males.
View Article and Find Full Text PDFProjection neurons are necessary for the maintenance of the mouse olfactory circuit.
Elife
December 2024
Department of Biology and Biological Engineering, California Institute of Technology, Pasadena, United States.
The assembly and maintenance of neural circuits is crucial for proper brain function. Although the assembly of brain circuits has been extensively studied, much less is understood about the mechanisms controlling their maintenance as animals mature. In the olfactory system, the axons of olfactory sensory neurons (OSNs) expressing the same odor receptor converge into discrete synaptic structures of the olfactory bulb (OB) called glomeruli, forming a stereotypic odor map.
View Article and Find Full Text PDFFirst report of acute, visceral, fatal toxoplasmosis in a naturally infected calf (Bos taurus).
Vet Parasitol
December 2024
Idexx Laboratories Hamilton, 20A Maui Street, Pukete, Hamilton 3200, New Zealand.
Cattle are considered resistant to clinical toxoplasmosis and viable Toxoplasma gondii is rarely isolated from bovine tissues. Currently, there is no histologically confirmed case of clinical toxoplasmosis in cattle. Here, the first confirmed case of acute toxoplasmosis in cattle is reported.
View Article and Find Full Text PDFExposure to a 0.9-GHz electromagnetic field on postnatal days 21-45 may trigger the renin-angiotensin system in male rat: a histological and biochemical study.
J Mol Histol
December 2024
Department of Histology and Embryology, Faculty of Medicine, Aksaray University, Aksaray, Türkiye.
Article Synopsis
- * Twelve rats were divided into two groups: one with no exposure (control) and one exposed to EMF for one hour daily over 25 days.
- * Findings showed that EMF exposure led to increased kidney size and weight, oxidative stress markers, and significant histopathological damage, suggesting that long-term EMF exposure may activate the RAS in kidney tissues.
Fast Processing of Electron Microscopic Specimen Preserved Ultrastructure of Glomeruli and Electron-Dense Deposits in Diagnostic Renal Biopsies: A Prospective and Retrospective Comparative Study.
Mod Pathol
November 2024
Department of Pathology, University of Iowa Hospitals and Clinics, Iowa City, Iowa; Department of Pathology, The Johns Hopkins Hospital, Baltimore, Maryland. Electronic address:
Article Synopsis
- - The optimization of electron microscopy (EM) tissue processing protocols is urgent due to the rising number of renal biopsies needing EM for accurate diagnoses, with traditional methods taking 48-52 hours compared to a faster 8-hour microwave-based method.
- - Concerns exist about the quality of the fast-processing EM (FEM) potentially affecting diagnoses; however, this study provides evidence that FEM produces comparably high-resolution images to the conventional EM (CEM).
- - Both prospective and retrospective analyses showed no significant differences between FEM and CEM in terms of image quality and structural features of kidney tissues, indicating that FEM can be a reliable alternative for quicker diagnoses.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!