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Prenatal Skin Cell Atlas reveals macrophages' role beyond immunity. | LitMetric

Prenatal Skin Cell Atlas reveals macrophages' role beyond immunity.

Immunol Cell Biol

Department of Immunology, School of Translational Medicine, Monash University, Melbourne, VIC, Australia.

Published: January 2025

AI Article Synopsis

  • A recent study by Gopee et al. reveals that macrophages have an unexpected role in human prenatal skin development beyond just their immune function.
  • By creating a detailed multi-omics single-cell atlas, the researchers illustrate how these innate immune cells contribute to crucial processes like hair follicle formation, scarless wound healing, and neurovascular development.
  • This research highlights the importance of understanding immune cells in developmental biology, potentially impacting future studies and therapies.

Article Abstract

In this article, we discuss a recently published study by Gopee et al., who have unveiled a surprising role for macrophages in human prenatal skin development, extending far beyond their traditional immune function. By constructing a comprehensive multi-omics single-cell atlas of human prenatal skin, they demonstrate that innate immune cells play a key role in hair follicle formation, scarless wound healing and neurovascular development.

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Source
http://dx.doi.org/10.1111/imcb.12837DOI Listing

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