AI Article Synopsis
- This study examined how body temperature relates to the 28-day mortality rates of sepsis patients in ICUs across the U.S. from 2014-2015.
- Researchers used various statistical models to analyze data from a large database of sepsis patients.
- The findings indicated that low body temperature (hypothermia) is linked to higher mortality rates, suggesting that further research on rewarming patients could be beneficial.
Article Abstract
Objective: This study explored the association between body temperature and 28-day septic ICU hospital mortality.
Design: Retrospective cohort analysis.
Setting: 208 ICUs in the United States.
Patients Or Participants: Sepsis patients from 2014-2015 eICU Collaborative Research Database.
Interventions: Binary logistic regression models, Generalized Additive Model (GAM), Two-Piece Binary Logistic Regression Model.
Main Variables Of Interest: Body temperature, 28-day inpatient mortality.
Results: Nonlinear relationship observed; hypothermia (≤36.67 ℃) associated with increased mortality (adjusted OR = 0.74, 95% CI: 0.70-0.80, p < 0.0001).
Conclusions: Hypothermia in sepsis correlates with higher mortality; rewarming's potential benefit warrants further exploration.
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| http://dx.doi.org/10.1016/j.medine.2024.08.004 | DOI Listing |
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