Isolation, structures, bioactivities, and applications of the polysaccharides from Boletus spp.: A review.

Boletus spp., the edible mushrooms distributed in Europe, Asia, and North America, have been widely used as food and medicinal ingredients worldwide. Bioactive polysaccharides are highly abundant in Boletus spp., as demonstrated by modern phytochemical studies. The isolation, chemical properties, and bioactivities of polysaccharides from Boletus spp. have long been attracted by academics worldwide. However, there is still a lack of systematic tracking of research progress on Boletus polysaccharides (BPs), which is essential for researchers to understand their potential and gain a deeper insight into their functional mechanisms. In this review, we summarized the recent development of BPs, including the extraction and purification methods, physiochemical and structural features, bioactivities and functional mechanisms, the structure-activity relationship, and the potential applications. This review aims to provide researchers with a comprehensive understanding of the current progress and potential of BPs to assist their further investigations.