Mental illness increases risk for obesity which is often attributed to medications. We assessed the impact of childhood maltreatment on body-mass-index (BMI) and obesity in N = 261 adult psychiatric inpatients and N = 81 controls. There was an increased risk for obesity in psychiatric inpatients compared to controls. Conditioned random forest regression revealed parental abuse at ages 4-5 and peer-related violence at 7-13 as crucial factors in BMI elevation among individuals with mental illness, while type of psychiatric diagnoses, and use of psychotropics were not. Recognizing this link may aid in understanding the mechanisms and the development of strategies to mitigate the risk.
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http://dx.doi.org/10.1016/j.psychres.2024.116264 | DOI Listing |
Braz J Psychiatry
December 2024
Pontifícia Universidade Católica do Rio de Janeiro (PUC-Rio), Rio de Janeiro, RJ, Brazil.
Objective: Disordered Eating Behaviors (DEB) are associated with dysfunctional changes in eating behavior, not meeting diagnostic criteria for eating disorders. DEB affects a significant percentage of individuals, yet it remains under-researched. The current study investigates the developmental trajectory and psychopathological correlates of DEB in children and adolescents in Brazil.
View Article and Find Full Text PDFScand J Occup Ther
January 2025
Department of Health Sciences, Mental Health, Activity and Participation (MAP), Lund University, Lund, Sweden.
Background: Existing research has shown that those ageing with severe mental illness face significant challenges in daily life. Attendance at community-based day centres (DCs) is offered to support daily structure and break isolation. However, little is known about the experiences of those receiving this type of support while transitioning into retirement age.
View Article and Find Full Text PDFSociol Health Illn
January 2025
Center for Public Policy and Health, Kent State University, Kent, Ohio, USA.
Fundamental Cause Theory (FCT) offers a unique middle range and longitudinal understanding of the lasting social causational relationships between certain social conditions and disease/death. In this research note, I argue that FCT should extend its outcome measures beyond physical disease and death into holistic health. I briefly review how FCT is evaluated, explore the proposed extension and discuss some operational and conceptual challenges using mental illness and positive mental health outcomes as exemplars.
View Article and Find Full Text PDFAnn Med
December 2025
Department of Anatomy, College of Medicine, King Khalid University, Abha, Saudi Arabia.
Background: Substance use disorders are multifaceted conditions influenced by both genetic and environmental factors. Serotonergic pathways are known to be involved in substance use disorder susceptibility, with genetic markers within serotonin receptor genes identified as potential risk factors.
Methods: To further explore this relationship, we conducted a study to investigate the association between several polymorphisms in five serotonin receptor genes (, , ) and substance use disorders (SUD) in Jordanian males by sequencing genotypes in 496 SUD patients and 496 healthy controls.
Methamphetamine (METH) is a highly addictive and dangerous drug that mainly affects neurotransmitters in the brain and leads to feelings of alertness and euphoria. The METH use can lead to addiction, which has become a worldwide problem, resulting in a slew of public health and safety issues. Recent studies showed that chronic METH use can lead to neurotoxicity, neuro-inflammation and oxidative stress which can lead to neuronal injury.
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