[Long-term efficacy and safety with sacituzumab govitecan in a patient with triple-negative breast cancer, multi-treated and high body mass index.].

Recenti Prog Med

Oncologia Casa Sollievo della Sofferenza, San Giovanni Rotondo (Foggia).

Published: November 2024

AI Article Synopsis

  • Metastatic triple negative breast cancer (mTNBC) is a severe type of breast cancer common in women under 50, and obesity at diagnosis worsens outcomes.* -
  • A new drug called sacituzumab govitecan (SG) has been approved for treating mTNBC, offering hope for improved life expectancy and quality of life.* -
  • A case study shows a young obese woman with mTNBC has had successful long-term treatment with SG, maintaining a good quality of life and social interactions for 20 months.*

Article Abstract

The metastatic triple negative breast cancer (mTNBC) represents a particularly aggressive form of breast cancer that frequently affects young women under the age of 50. Obesity at the time of breast cancer diagnosis is associated with a worse prognosis. Compared to the recent past, increasing life expectancy and quality of life for patients with mTNBC is now a possible challenge, thanks to a new drug, sacituzumab govitecan (SG), an anti-Trop-2 antibody drug conjugate approved as monotherapy for the treatment of these patients. The presented clinical case documents the efficacy and safety of long-term treatment with SG in an obese young woman with mTNBC who has already undergone multiple treatments. The patient is still responding after 20 months of treatment with good quality of life and social interactions.

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Source
http://dx.doi.org/10.1701/4365.43617DOI Listing

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