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Concomitant diagnosis of Trypanosoma cruzi and HIV in a patient with neurologic manifestations: A case report. | LitMetric

Concomitant diagnosis of Trypanosoma cruzi and HIV in a patient with neurologic manifestations: A case report.

Braz J Infect Dis

Departamento de Parasitología, Facultad de Microbiología, Universidad de Costa Rica, San José, Costa Rica; Centro de Investigación en Enfermedades Tropicales (CIET), Universidad de Costa Rica, San José, Costa Rica. Electronic address:

Published: December 2024

American trypanosomiasis or Chagas disease is a vector-borne infection caused by the protozoan parasite Trypanosoma cruzi, characterized by acute and chronic phases; reactivations due to immunosuppression can occur. In this case report, we confirm the presence of trypomastigotes of T. cruzi in a patient with neurologic manifestations. For this purpose, a battery of techniques, including direct examination of cerebrospinal fluid, Giemsa stains, sample cultures, serology and molecular techniques were employed. The patient was treated with nifurtimox for 6 months and started antiretroviral therapy as the concomitant diagnosis of HIV was also performed, showing no sequelae nor adverse effects. A follow-up of the patient´s health status was performed for 42 months.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11609539PMC
http://dx.doi.org/10.1016/j.bjid.2024.104478DOI Listing

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