Introduction And Importance: Rathke's cleft cyst (RCC) are non-malignant lesions arising from remnants of Rathke's pouch in the pituitary gland. Apoplexy is seen commonly in pituitary macroadenomas but very rarely in RCCs.
Case Presentation: A 30-year-old male presented with a severe headache and vomiting. Imaging revealed an enlarged pituitary gland with possible hemorrhage in a RCC. The cyst was evacuated with endonasal transsphenoidal surgery, and histology confirmed RCC. Follow-up imaging showed complete cyst resolution, although he required levothyroxine for hypothyroidism.
Clinical Discussion: The occurrence of hemorrhage within RCCs, although rare, mimics pituitary tumor apoplexy often complicating the diagnosis. The management is similar to pituitary tumor apoplexy, primarily involving surgical intervention. Postoperative care may require long-term hormonal replacement therapy in a significant number of patients.
Conclusion: This report underscores the importance of considering RCC in the differential diagnoses of pituitary lesions with hemorrhage with promising surgical outcome.
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http://dx.doi.org/10.1016/j.ijscr.2024.110571 | DOI Listing |
J Clin Neurosci
January 2025
Department of Neurosurgery, Hadassah Hebrew University Medical Center, Jerusalem, Israel.
Background: Craniopharyngiomas are epithelial tumors derived from the remnants of the Rathke pouch, while Rathke cleft cysts (RCC) are benign cystic lesions originating from the Rathke pouch itself [1]. Rathke cleft cysts comprise 10-15% of the hypophyseal tumors, while craniopharyngiomas are relatively rare, comprising only 2-5% of intracranial tumors [2]. Both located in the sellar and parasellar regions and share clinical symptoms including headache, visual disturbances, and endocrine dysfunction [3].
View Article and Find Full Text PDFNeurosurg Rev
December 2024
Department of Neurosurgery, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Rathke's cleft cysts (RCCs) are benign, cystic lesions that account for less than 5% of cases in the pediatric population. While asymptomatic RCCs often require only conservative management, symptomatic cases may necessitate surgical intervention. Advances in surgical techniques have improved the safety of these procedures.
View Article and Find Full Text PDFPituitary
December 2024
Department of Diabetes and Endocrinology, St Vincent's Hospital Sydney, Darlinghurst, NSW, Australia.
Purpose: Rathke's cleft cysts (RCC) are present in up to 20% of autopsy studies but only a minority necessitate surgical treatment. Inflammation of RCC is thought to be significant in three processes: the development of classical symptoms, a predisposition to rupture or apoplexy, and increasing the rate of RCC recurrence. We aim to characterize clinical presentation, histological and radiological findings in patients with surgically managed RCC.
View Article and Find Full Text PDFPituitary
December 2024
Department of Neurosurgery, Monash Health, Melbourne, Australia.
Neurol India
November 2024
Department of Neurosurgery, PGIMER, Chandigarh, India.
Proper skull base repair is essential in preventing postoperative cerebrospinal fluid (CSF) leak following endonasal endoscopic skull base surgery. Direct suturing of the skull base dura is desirable but difficult. Here, we discuss the effectiveness of endoscopic suturing of skull base dura in cases of skull base lesions with intraoperative CSF leak.
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